Tag | Content |
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CPLM ID | CPLM-003480 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Negative regulator of flagellin synthesis |
Protein Synonyms/Alias | Anti-sigma-28 factor |
Gene Name | flgM |
Gene Synonyms/Alias | b1071; JW1058 |
Created Date | July 27, 2013 |
Organism | Escherichia coli (strain K12) |
NCBI Taxa ID | 83333 |
Lysine Modification | Position | Peptide | Type | References |
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10 | IDRTSPLKPVSTVQP | acetylation | [1] |
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Reference | [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli. Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C. Mol Cell. 2013 Jul 25;51(2):265-72. [ PMID: 23830618] |
Functional Description | Responsible for the coupling of flagellin expression to flagellar assembly by preventing expression of the flagellin genes when a component of the middle class of proteins is defective. It negatively regulates flagellar genes by inhibiting the activity of FliA by directly binding to FliA. |
Sequence Annotation | |
Keyword | Bacterial flagellum biogenesis; Complete proteome; Reference proteome; Repressor; Transcription; Transcription regulation. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 97 AA |
Protein Sequence | MSIDRTSPLK PVSTVQPRET TDAPVTNSRA AKTTASTSTS VTLSDAQAKL MQPGSSDINL 60 ERVEALKLAI RNGELKMDTG KIADALINEA QQDLQSN 97 |
Gene Ontology | GO:0043064; P:flagellum organization; IEA:UniProtKB-KW. GO:0045892; P:negative regulation of transcription, DNA-dependent; IEA:InterPro. GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |