CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-016533
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Golgi resident protein GCP60 
Protein Synonyms/Alias
 Acyl-CoA-binding domain-containing protein 3; Golgi complex-associated protein 1; GOCAP1; Golgi phosphoprotein 1; GOLPH1; PBR- and PKA-associated protein 7; Peripheral benzodiazepine receptor-associated protein PAP7 
Gene Name
 Acbd3 
Gene Synonyms/Alias
 Gcp60; Pap7 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
383QIKDFKEKIRQDADSubiquitination[1]
504GRGVYLLKFDNSYSLubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
 Involved in the maintenance of Golgi structure by interacting with giantin, affecting protein transport between the endoplasmic reticulum and Golgi (By similarity). Involved in hormone-induced steroid biosynthesis in testicular Leydig cells. 
Sequence Annotation
 DOMAIN 80 171 ACB.
 DOMAIN 381 523 GOLD.
 MOD_RES 13 13 Phosphoserine (By similarity).
 MOD_RES 20 20 Phosphoserine (By similarity).
 MOD_RES 40 40 Phosphoserine (By similarity).  
Keyword
 Coiled coil; Complete proteome; Golgi apparatus; Lipid biosynthesis; Lipid metabolism; Membrane; Mitochondrion; Phosphoprotein; Reference proteome; Steroid biosynthesis. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 525 AA 
Protein Sequence
MAAQLNVEQL EVSLDGLTLS PDSEERPGAE GAPPQTPPSS APGNGLGSGA SGQQREPGEA 60
AAEGAAEEAR RMEQHWGFGL EELYGLALRF YKIKDGKAFH PTYEEKLKFV ALHKQVLLGP 120
YNPDTSPEVG FFDVLGNDRR REWAALGNMS KEDAMVEFVK LLNKCCPLLS AYVASHRIEK 180
EEEEKRRKAE EERRQREEEE RERLQKEEEK RKREKEDRLR REEEERRRIE EERLRLEQQK 240
QQIMAALNSQ TAVQFQQYAA QQYPGNYEQQ QILIRQLQEQ HYQQYMQQLY QVQLAQQQAA 300
LQKQQEVVMA GASLPASSKV NTAGASDTLS VNGQAKTHTE NSEKVLEPEA AEEALENGPK 360
DSLPVIAAPS MWTRPQIKDF KEKIRQDADS VITVRRGEVV TVRVPTHEEG SYLFWEFATD 420
SYDIGFGVYF EWTDSPNAAV SVHVSESSDE EEEEEENVTC EEKAKKNANK PLLDEIVPVY 480
RRDCHEEVYA GSHQYPGRGV YLLKFDNSYS LWRSKSVYYR VYYTR 525 
Gene Ontology
 GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
 GO:0016021; C:integral to membrane; IEA:InterPro.
 GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
 GO:0000062; F:fatty-acyl-CoA binding; IEA:InterPro.
 GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW.
 GO:0006810; P:transport; IEA:InterPro. 
Interpro
 IPR022408; Acyl-CoA-binding_prot_CS.
 IPR000582; Acyl-CoA-binding_protein.
 IPR014352; FERM/acyl-CoA-bd_prot_3-hlx.
 IPR009038; GOLD. 
Pfam
 PF00887; ACBP
 PF13897; GOLD_2 
SMART
  
PROSITE
 PS00880; ACB_1
 PS51228; ACB_2
 PS50866; GOLD 
PRINTS