UniProt Accession

 TM222_HUMAN; Q9H0R3; D3DPL6; Q53HD8; Q5FVE9 

Genbank Protein ID

 FO393419; CH471059; CH471059; BC011579; BC090039; AL136683; AK222642 

Genbank Nucleotide ID

 EAX07764.1; EAX07766.1; AAH11579.2; AAH90039.1; CAB66618.1; BAD96362.1 

Protein Name

 Transmembrane protein 222 

Protein Synonyms/Alias

  

Gene Name

 TMEM222 

Gene Synonyms/Alias

 C1orf160 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
101	EDNMAFGKPAKYWKL	ubiquitination	[1, 2]
104	MAFGKPAKYWKLDPA	ubiquitination	[2]
107	GKPAKYWKLDPAQVY	ubiquitination	[1]
133	HDASEEYKHRMHNLC	ubiquitination	[1, 2]

Reference

 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 

Functional Description

  

Sequence Annotation

  

Keyword

 Alternative splicing; Complete proteome; Membrane; Reference proteome; Transmembrane; Transmembrane helix. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 208 AA 

Protein Sequence

Gene Ontology

 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. 

Interpro

 IPR008496; DUF778. 

Pfam

 PF05608; DUF778 

SMART

  

PROSITE

  

PRINTS