CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-017287
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Pantothenate kinase 1 
Protein Synonyms/Alias
 mPank; mPank1; Pantothenic acid kinase 1 
Gene Name
 Pank1 
Gene Synonyms/Alias
 Pank 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
206KLVYFEPKDITAEEEubiquitination[1]
221QEEVENLKSIRKYLTubiquitination[1]
225ENLKSIRKYLTSNTAubiquitination[1]
235TSNTAYGKTGIRDVHubiquitination[1]
423GDSTNVDKLVKDIYGubiquitination[1]
426TNVDKLVKDIYGGDYubiquitination[1]
453SFGNMMSKEKRESISubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
 Plays a role in the physiological regulation of the intracellular CoA concentration. 
Sequence Annotation
 BINDING 367 367 Acetyl-CoA (By similarity).
 BINDING 370 370 Acetyl-CoA (By similarity).
 BINDING 382 382 Acetyl-CoA (By similarity).
 MOD_RES 165 165 Phosphoserine (By similarity).  
Keyword
 Alternative splicing; ATP-binding; Coenzyme A biosynthesis; Complete proteome; Kinase; Nucleotide-binding; Phosphoprotein; Reference proteome; Transferase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 548 AA 
Protein Sequence
MRGRRAPRPG STEVPAAARD ADTLRARAAS PVRGAQLAED VGTPTGGGEE RRGHQLPTAA 60
PRLRESKPQG GSEDRGTADR DLQRGCQSRS PRTAPPVPGM GDRGAQHERA ALQSPGAPEG 120
AAAAVNGLLH NGFHPSAASS RDPPAPRFQL PSELQPQPLF AQHDSPAKKC RLRRRMDSGR 180
KNRPPFPWFG MDIGGTLVKL VYFEPKDITA EEEQEEVENL KSIRKYLTSN TAYGKTGIRD 240
VHLELKNLTM CGRKGNLHFI RFPTCAMHLF IQMGSEKNFS SLHTTLCATG GGAFKFEEDF 300
RMIADLQLHK LDELDCLIQG LLYVDSVGFN GKPECYYFEN PTNPELCQKK PYCLDNPYPM 360
LLVNMGSGVS ILAVYSKDNY KRVTGTSLGG GTFLGLCCLL TGCETFEEAL DMAAKGDSTN 420
VDKLVKDIYG GDYERFGLQG SAVASSFGNM MSKEKRESIS KEDLARATLV TITNNIGSIA 480
RMCALNENID RVVFVGNFLR INMVSMKLLA YAMDFWSKGQ LKALFLEHEG YFGAVGALLE 540
LFKMTDTQ 548 
Gene Ontology
 GO:0071944; C:cell periphery; IDA:MGI.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0004594; F:pantothenate kinase activity; IDA:MGI.
 GO:0015937; P:coenzyme A biosynthetic process; TAS:MGI. 
Interpro
 IPR004567; Type_II_PanK. 
Pfam
 PF03630; Fumble 
SMART
  
PROSITE
  
PRINTS