UniProt Accession

 CD7_HUMAN; P09564 

Genbank Protein ID

 X06180; M37271; BT006696; BC009293; BC013297; D00749 

Genbank Nucleotide ID

 CAA29546.1; AAA51953.1; AAP35342.1; AAH09293.1; AAH13297.1; BAA00646.1 

Protein Name

 T-cell antigen CD7 

Protein Synonyms/Alias

 GP40; T-cell leukemia antigen; T-cell surface antigen Leu-9; TP41; CD7 

Gene Name

 CD7 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
214	KLCSWRDKNSAACVV	ubiquitination	[1]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 

Functional Description

 Not yet known. 

Sequence Annotation

 DOMAIN 26 130 Ig-like.
 REPEAT 145 153 1.
 REPEAT 154 162 2.
 REPEAT 163 171 3.
 REPEAT 172 180 4.
 REGION 145 180 4 X 9 AA tandem repeats, potential spacer
 LIPID 198 198 S-palmitoyl cysteine.
 CARBOHYD 45 45 N-linked (GlcNAc...).
 CARBOHYD 96 96 N-linked (GlcNAc...).
 DISULFID 35 142 Potential.
 DISULFID 48 114 Potential.  

Keyword

 Adaptive immunity; Complete proteome; Disulfide bond; Glycoprotein; Immunity; Immunoglobulin domain; Lipoprotein; Membrane; Palmitate; Polymorphism; Receptor; Reference proteome; Repeat; Signal; Transmembrane; Transmembrane helix. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 240 AA 

Protein Sequence

Gene Ontology

 GO:0016021; C:integral to membrane; TAS:UniProtKB.
 GO:0005886; C:plasma membrane; TAS:ProtInc.
 GO:0004872; F:receptor activity; TAS:UniProtKB.
 GO:0048873; P:homeostasis of number of cells within a tissue; IEA:Compara.
 GO:0006955; P:immune response; TAS:UniProtKB.
 GO:0042110; P:T cell activation; TAS:UniProtKB.
 GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; NAS:UniProtKB. 

Interpro

 IPR007110; Ig-like_dom.
 IPR013783; Ig-like_fold.
 IPR003599; Ig_sub.
 IPR013106; Ig_V-set. 

Pfam

 PF07686; V-set 

SMART

 SM00409; IG 

PROSITE

 PS50835; IG_LIKE 

PRINTS