| Tag | Content |
|---|
| CPLM ID | CPLM-010981 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Pre-mRNA-splicing factor SLU7 |
Protein Synonyms/Alias | Synthetic lethal with U2 snRNA protein 17; Synthetic lethal with U5 snRNA protein 7 |
Gene Name | SLU7 |
Gene Synonyms/Alias | SLT17; YDR088C; D4483 |
Created Date | July 27, 2013 |
Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
NCBI Taxa ID | 559292 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 180 | RWYGYSGKEYNELIS | acetylation | [1] | | 335 | VLVANPTKYEYLKKK | acetylation | [1] |
|
Reference | [1] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae. Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C. Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [ PMID: 22865919] |
Functional Description | Essential protein involved in the second catalytic step of pre-mRNA splicing. Involved in the selection of 3'-type splice sites; this selection could be done via a 3'-splice site-binding factor, PRP16. |
Sequence Annotation | ZN_FING 120 137 CCHC-type.
REGION 200 224 Interaction with PRP8.
MOD_RES 120 120 Phosphoserine.
MOD_RES 212 212 Phosphothreonine. |
Keyword | Complete proteome; Glycoprotein; Metal-binding; mRNA processing; mRNA splicing; Nucleus; Phosphoprotein; Reference proteome; Spliceosome; Zinc; Zinc-finger. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 382 AA |
Protein Sequence | MNNNSRNNEN RSTINRNKRQ LQQAKEKNEN IHIPRYIRNQ PWYYKDTPKE QEGKKPGNDD 60
TSTAEGGEKS DYLVHHRQKA KGGALDIDNN SEPKIGMGIK DEFKLIRPQK MSVRDSHSLS 120
FCRNCGEAGH KEKDCMEKPR KMQKLVPDLN SQKNNGTVLV RATDDDWDSR KDRWYGYSGK 180
EYNELISKWE RDKRNKIKGK DKSQTDETLW DTDEEIELMK LELYKDSVGS LKKDDADNSQ 240
LYRTSTRLRE DKAAYLNDIN STESNYDPKS RLYKTETLGA VDEKSKMFRR HLTGEGLKLN 300
ELNQFARSHA KEMGIRDEIE DKEKVQHVLV ANPTKYEYLK KKREQEETKQ PKIVSIGDLE 360
ARKVDGTKQS EEQRNHLKDL YG 382 |
Gene Ontology | GO:0005681; C:spliceosomal complex; IDA:SGD. GO:0003676; F:nucleic acid binding; IEA:InterPro. GO:0008270; F:zinc ion binding; IEA:InterPro. GO:0000350; P:generation of catalytic spliceosome for second transesterification step; IDA:SGD. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |