UniProt Accession

 ATP5I_MOUSE; Q06185; P70342 

Genbank Protein ID

 S52977; U59283; BC028438 

Genbank Nucleotide ID

 AAB24947.1; AAC52713.1; AAH28438.1 

Protein Name

 ATP synthase subunit e, mitochondrial 

Protein Synonyms/Alias

 ATPase subunit e 

Gene Name

 Atp5i 

Gene Synonyms/Alias

 Atp5k; Lfm-1; Lfm1 

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
34	AKRYSYLKPRAEEER	acetylation	[1]
48	RRIAAEEKKRLDELK	acetylation	[2]
71	AQDDSILK*******	acetylation	[2]

Reference

 [1] Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways.
 Rardin MJ, Newman JC, Held JM, Cusack MP, Sorensen DJ, Li B, Schilling B, Mooney SD, Kahn CR, Verdin E, Gibson BW.
 Proc Natl Acad Sci U S A. 2013 Apr 16;110(16):6601-6. [PMID: 23576753]
 [2] Quantification of mitochondrial acetylation dynamics highlights prominent sites of metabolic regulation.
 Still AJ, Floyd BJ, Hebert AS, Bingman CA, Carson JJ, Gunderson DR, Dolan BK, Grimsrud PA, Dittenhafer-Reed KE, Stapleton DS, Keller MP, Westphall MS, Denu JM, Attie AD, Coon JJ, Pagliarini DJ.
 J Biol Chem. 2013 Jul 17;. [PMID: 23864654] 

Functional Description

 Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane. 

Sequence Annotation

 MOD_RES 32 32 Phosphotyrosine.  

Keyword

 ATP synthesis; CF(0); Complete proteome; Direct protein sequencing; Hydrogen ion transport; Ion transport; Membrane; Mitochondrion; Mitochondrion inner membrane; Phosphoprotein; Reference proteome; Transport. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 71 AA 

Protein Sequence

Gene Ontology

 GO:0005753; C:mitochondrial proton-transporting ATP synthase complex; ISS:UniProtKB.
 GO:0000276; C:mitochondrial proton-transporting ATP synthase complex, coupling factor F(o); IEA:Compara.
 GO:0016887; F:ATPase activity; IEA:Compara.
 GO:0015078; F:hydrogen ion transmembrane transporter activity; IEA:InterPro.
 GO:0015986; P:ATP synthesis coupled proton transport; IEA:InterPro. 

Interpro

 IPR008386; ATPase_F0-cplx_esu_mt. 

Pfam

 PF05680; ATP-synt_E 

SMART

  

PROSITE

  

PRINTS