CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-039343
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Glutamate receptor ionotropic, kainate 1 
Protein Synonyms/Alias
 Glutamate receptor, ionotropic, kainate 1, isoform CRA_b 
Gene Name
 Grik1 
Gene Synonyms/Alias
 rCG_58820 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
380TGRITFNKTDGLRKDacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Cell junction; Cell membrane; Complete proteome; Ion channel; Ion transport; Ligand-gated ion channel; Membrane; Postsynaptic cell membrane; Receptor; Reference proteome; Synapse; Transmembrane; Transmembrane helix; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 949 AA 
Protein Sequence
MERSTVLIQP GLWTRDTSWT LLYFLCYILP QTSPQVLRIG GIFETVENEP VNVEELAFKF 60
AVTSINRNRT LMPNTTLTYD IQRINLFDSF EASRRACDQL ALGVAALFGP SHSSSVSAVQ 120
SICNALEVPH IQTRWKHPSV DSRDLFYINL YPDYAAISRA VLDLVLYYNW KTVTVVYEDS 180
TGLIRLQELI KAPSRYNIKI KIRQLPPANK DAKPLLKEMK KSKEFYVIFD CSHETAAEIL 240
KQILFMGMMT EYYHYFFTTL DLFALDLELY RYSGVNMTGF RLLNIDNPHV SSIIEKWSME 300
RLQAPPRPET GLLDGMMTTE AALMYDAVYM VAIASHRASQ LTVSSLQCHR HKPWRLGPRF 360
MNLIKEARWD GLTGRITFNK TDGLRKDFDL DIISLKEEGT EKASGEVSKH LYKVWKKIGI 420
WNSNSGLNMT DGNRDRSNNI TDSLANRTLI VTTILEEPYV MYRKSDKPLY GNDRFEGYCL 480
DLLKELSNIL GFLYDVKLVP DGKYGAQNDK GEWNGMVKEL IDHRADLAVA PLTITYVREK 540
VIDFSKPFMT LGISILYRKP NGTNPGVFSF LNPLSPDIWM YVLLACLGVS CVLFVIARFT 600
PYEWYNPHPC NPDSDVVENN FTLLNSFWFG VGALMQQGSE LMPKALSTRI VGGIWWFFTL 660
IIISSYTANL AAFLTVERME SPIDSADDLA KQTKIEYGAV RDGSTMTFFK KSKISTYEKM 720
WAFMSSRQQS ALVKNSDEGI QRVLTTDYAL LMESTSIEYV TQRNCNLTQI GGLIDSKGYG 780
VGTPIGSPYR DKITIAILQL QEEGKLHMMK EKWWRGNGCP EEDSKEASAL GVENIGGIFI 840
VLAAGLVLSV FVAIGEFLYK SRKNNDVEQK GKSSRLRFYF RNKVRFHGSK KESLGVEKCL 900
SFNAIMEELG ISLKNQKKLK KKSRTKGKSS FTSILTCHQR RTQRKETVA 949 
Gene Ontology
 GO:0030054; C:cell junction; IEA:UniProtKB-KW.
 GO:0030425; C:dendrite; IEA:Compara.
 GO:0032983; C:kainate selective glutamate receptor complex; IEA:Compara.
 GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-KW.
 GO:0042734; C:presynaptic membrane; IEA:Compara.
 GO:0005234; F:extracellular-glutamate-gated ion channel activity; IEA:InterPro.
 GO:0015277; F:kainate selective glutamate receptor activity; IEA:Compara.
 GO:0030534; P:adult behavior; IEA:Compara.
 GO:0048266; P:behavioral response to pain; IEA:Compara.
 GO:0035235; P:ionotropic glutamate receptor signaling pathway; IEA:GOC.
 GO:0051967; P:negative regulation of synaptic transmission, glutamatergic; IEA:Compara.
 GO:0014054; P:positive regulation of gamma-aminobutyric acid secretion; IEA:Compara.
 GO:0032230; P:positive regulation of synaptic transmission, GABAergic; IEA:Compara.
 GO:0060079; P:regulation of excitatory postsynaptic membrane potential; IEA:Compara.
 GO:0060080; P:regulation of inhibitory postsynaptic membrane potential; IEA:Compara.
 GO:0035249; P:synaptic transmission, glutamatergic; IEA:Compara. 
Interpro
 IPR001828; ANF_lig-bd_rcpt.
 IPR019594; Glu_rcpt_Glu/Gly-bd.
 IPR001320; Iontro_glu_rcpt.
 IPR001508; NMDA_rcpt. 
Pfam
 PF01094; ANF_receptor
 PF00060; Lig_chan
 PF10613; Lig_chan-Glu_bd 
SMART
 SM00918; Lig_chan-Glu_bd
 SM00079; PBPe 
PROSITE
  
PRINTS
 PR00177; NMDARECEPTOR.