| Tag | Content |
|---|
| CPLM ID | CPLM-016733 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Tubulin-specific chaperone cofactor E-like protein |
Protein Synonyms/Alias | Leucine-rich repeat-containing protein 35 |
Gene Name | Tbcel |
Gene Synonyms/Alias | Lrrc35 |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 254 | LRSISLHKSGLQSWE | ubiquitination | [1] | | 347 | ELITKYGKLEPLAEV | ubiquitination | [1] | | 387 | DQTVAELKKQLKTLV | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | Acts as a regulator of tubulin stability (By similarity). |
Sequence Annotation | REPEAT 73 98 LRR 1.
REPEAT 99 123 LRR 2.
REPEAT 124 147 LRR 3.
REPEAT 152 173 LRR 4.
REPEAT 175 196 LRR 5.
REPEAT 201 222 LRR 6.
REPEAT 228 249 LRR 7.
DOMAIN 262 303 LRRCT.
DOMAIN 334 424 Ubiquitin-like.
MOD_RES 41 41 Phosphoserine. |
Keyword | Alternative splicing; Coiled coil; Complete proteome; Cytoplasm; Cytoskeleton; Leucine-rich repeat; Phosphoprotein; Reference proteome; Repeat. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 424 AA |
Protein Sequence | MASEVNASSP ALNFSEKKMD QPSGRSFMQV LCEKYSPENF PYRRGPGVGV HVPATPQGSP 60
MKDRLNLPSV LVLNSCGITC AGDEREIAAF CAHVSELDLS DNKLQDWHEV SKIVSNVPQL 120
EFLNLSSNPL SLSVLERTCA GSFSGVRKLV LNNSKASWET VHTILQELPE LEELFLCLND 180
YETVSCPSVC CHSLKLLHIT DNNLQDWTEI RKLGVMFPSL DTLVLANNHL NAIEEPADSL 240
ARLFPNLRSI SLHKSGLQSW EDIDKLNSFP KLEEVRLLGI PLLQPYTTEE RRKLVVARLP 300
SVSKLNGSVV TDGEREDSER FFIRYYVDVP QEEVPFRYHE LITKYGKLEP LAEVDLRPQS 360
SAKVEVHFND QVEEMSIRLD QTVAELKKQL KTLVQLPTSS MLLYYFDHEA PFGPEEMKYS 420
SRALHSFGIR DGDKIFVESK TK 442 |
Gene Ontology | |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |