| Tag | Content |
|---|
| CPLM ID | CPLM-012940 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 |
Protein Synonyms/Alias | BAI1-associated protein 2-like protein 1 |
Gene Name | Baiap2l1 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Rattus norvegicus (Rat) |
NCBI Taxa ID | 10116 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 98 | ENFKKFHKEIIHELE | acetylation | [1] | | 106 | EIIHELEKKTELDVK | acetylation | [1] |
|
Reference | [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns. Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV. Cell Rep. 2012 Aug 30;2(2):419-31. [ PMID: 22902405] |
Functional Description | May function as adapter protein. Involved in the formation of clusters of actin bundles. Plays a role in the reorganization of the actin cytoskeleton in response to bacterial infection (By similarity). |
Sequence Annotation | DOMAIN 1 249 IMD.
DOMAIN 340 403 SH3.
REGION 488 516 Binds F-actin (By similarity).
MOD_RES 248 248 Phosphothreonine (By similarity).
MOD_RES 257 257 Phosphothreonine (By similarity).
MOD_RES 261 261 Phosphoserine (By similarity).
MOD_RES 281 281 Phosphoserine (By similarity).
MOD_RES 330 330 Phosphoserine (By similarity).
MOD_RES 332 332 Phosphoserine (By similarity).
MOD_RES 413 413 Phosphothreonine (By similarity). |
Keyword | Actin-binding; Alternative splicing; Coiled coil; Complete proteome; Cytoplasm; Cytoskeleton; Phosphoprotein; Reference proteome; SH3 domain. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 516 AA |
Protein Sequence | MSRGPEEVNR LTENTYRNVV EQFNPGLRNL INLGKNYEKA VNAMILAGKA YYDGVAKIGE 60
IATGSPVSTE LGHVLIEISS THKKLNETLD ENFKKFHKEI IHELEKKTEL DVKYMNATLK 120
RYQAEHRNKL DSLEKSQAEL KKIRRKSQGG RNALKYEHKE IEYVETVTSR QSEIQKFIAD 180
GCKEALLEEK RRFCFLVDKH CSFASHIHRY HLQSAELLNS KLPRWQETCC DATKVPEKIM 240
NMIEEIKTPI STPVSGTPQP SPMTERSKMI GKDYDTLSKY SPKMPPAPSV KAYTSPLIDM 300
FNNPATAGQS AEKTNNSTAN TGDDPSLQRS VSVATGLNMM KKQKVKTIFP HTAGNNKTLL 360
SFAQGDVLTL LIPEEKDGWL YGEHDTTKVR GWFPSSYTKL LEENMKEAMS VPTPSSAPVR 420
SISTVDLTEK SSVVIPPPDY LECLSMGATS DKRADAAKIP STSTFKAPVP RPDATSTSPS 480
DSNGTAKPPF LSGENPFATV KLRPTVTNDR SAPIIR 516 |
Gene Ontology | GO:0015629; C:actin cytoskeleton; IEA:Compara. GO:0030054; C:cell junction; IEA:Compara. GO:0005829; C:cytosol; ISS:UniProtKB. GO:0005634; C:nucleus; IEA:Compara. GO:0005886; C:plasma membrane; IEA:Compara. GO:0070064; F:proline-rich region binding; ISS:UniProtKB. GO:0046847; P:filopodium assembly; IEA:InterPro. GO:2000251; P:positive regulation of actin cytoskeleton reorganization; ISS:UniProtKB. GO:0030838; P:positive regulation of actin filament polymerization; ISS:UniProtKB. GO:0009617; P:response to bacterium; ISS:UniProtKB. GO:0007165; P:signal transduction; IEA:InterPro. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |