CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-036295
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 E3 SUMO-protein ligase PIAS4 
Protein Synonyms/Alias
  
Gene Name
 Pias4 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
118GLGRLPTKTLKPEVRacetylation[1]
Reference
 [1] SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways.
 Park J, Chen Y, Tishkoff DX, Peng C, Tan M, Dai L, Xie Z, Zhang Y, Zwaans BM, Skinner ME, Lombard DB, Zhao Y.
 Mol Cell. 2013 Jun 27;50(6):919-30. [PMID: 23806337] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 297 AA 
Protein Sequence
MAAELVEAKN MVMSFRVSDL QMLLGFVGRS KSGLKHELVT RALQLVQFDC SPELFKKIKE 60
LYETRYAKKS AEPGPQAPRP LDPLALHSMP RTPLSGPTVD YPVLYGKYLN GLGRLPTKTL 120
KPEVRLVKLP FFNMLDELLK PTELVPQSAE KLQESPCIFA LTPRQVEMIR NSRELQPGVK 180
AVQVVLRICY SDTSCPQEDQ YPPNIAVKVN HSYCSVPGYY PSNKPGVEPK RPCRPINLTH 240
LMYLSSATNR ITVTWGNYGK SYSVALYLVR QLTSSDLLQR LKTIGVKHPE LCKALGE 297 
Gene Ontology
 GO:0016363; C:nuclear matrix; IDA:MGI.
 GO:0003677; F:DNA binding; IDA:MGI.
 GO:0019789; F:SUMO ligase activity; IDA:MGI.
 GO:0003714; F:transcription corepressor activity; IDA:MGI.
 GO:0007259; P:JAK-STAT cascade; ISA:MGI.
 GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:MGI.
 GO:0016925; P:protein sumoylation; IDA:MGI. 
Interpro
 IPR027224; PIAS4.
 IPR023321; PINIT.
 IPR003034; SAP_dom. 
Pfam
 PF14324; PINIT
 PF02037; SAP 
SMART
 SM00513; SAP 
PROSITE
 PS51466; PINIT
 PS50800; SAP 
PRINTS