| Tag | Content |
|---|
| CPLM ID | CPLM-000022 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Armadillo repeat protein deleted in velo-cardio-facial syndrome |
Protein Synonyms/Alias | |
Gene Name | ARVCF |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 797 | AATAKGPKGALSPGG | ubiquitination | [1] | | 815 | STLPLVDKSLEGEKT | ubiquitination | [1] | | 821 | DKSLEGEKTGSRDVI | ubiquitination | [1] |
|
Reference | [1] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization. Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW. Nature. 2013 Apr 18;496(7445):372-6. [ PMID: 23503661] |
Functional Description | Involved in protein-protein interactions at adherens junctions. |
Sequence Annotation | REPEAT 348 387 ARM 1.
REPEAT 390 429 ARM 2.
REPEAT 433 467 ARM 3.
REPEAT 468 508 ARM 4.
REPEAT 526 565 ARM 5.
REPEAT 575 622 ARM 6.
REPEAT 646 686 ARM 7.
REPEAT 699 738 ARM 8.
REPEAT 739 781 ARM 9.
REPEAT 782 826 ARM 10.
MOTIF 607 623 Nuclear localization signal (Potential).
MOD_RES 267 267 Phosphoserine (By similarity).
MOD_RES 642 642 Phosphothreonine (By similarity).
MOD_RES 864 864 Phosphoserine.
MOD_RES 871 871 Phosphoserine.
MOD_RES 872 872 Phosphothreonine. |
Keyword | Alternative splicing; Cell adhesion; Coiled coil; Complete proteome; Phosphoprotein; Polymorphism; Reference proteome; Repeat. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 962 AA |
Protein Sequence | MPAELRQEQS PGSQASLATM PEAPDVLEET VTVEEDPGTP TSHVSIVTSE DGTTRRTETK 60
VTKTVKTVTT RTVRQVPVGP DGLPLLDGGP PLGPFADGAL DRHFLLRGGG PVATLSRAYL 120
SSGGGFPEGP EPRDSPSYGS LSRGLGMRPP RAGPLGPGPG DGCFTLPGHR EAFPVGPEPG 180
PPGGRSLPER FQAEPYGLED DTRSLAADDE GGPELEPDYG TATRRRPECG RGLHTRAYED 240
TADDGGELAD ERPAFPMVTA PLAQPERGSM GSLDRLVRRS PSVDSARKEP RWRDPELPEV 300
LAMLRHPVDP VKANAAAYLQ HLCFENEGVK RRVRQLRGLP LLVALLDHPR AEVRRRACGA 360
LRNLSYGRDT DNKAAIRDCG GVPALVRLLR AARDNEVREL VTGTLWNLSS YEPLKMVIID 420
HGLQTLTHEV IVPHSGWERE PNEDSKPRDA EWTTVFKNTS GCLRNVSSDG AEARRRLREC 480
EGLVDALLHA LQSAVGRKDT DNKSVENCVC IMRNLSYHVH KEVPGADRYQ EAEPGPLGSA 540
VGSQRRRRDD ASCFGGKKAK EEWFHQGKKD GEMDRNFDTL DLPKRTEAAK GFELLYQPEV 600
VRLYLSLLTE SRNFNTLEAA AGALQNLSAG NWMWATYIRA TVRKERGLPV LVELLQSETD 660
KVVRAVAIAL RNLSLDRRNK DLIGSYAMAE LVRNVRNAQA PPRPGACLEE DTVVAVLNTI 720
HEIVSDSLDN ARSLLQARGV PALVALVASS QSVREAKAAS HVLQTVWSYK ELRGTLQKDG 780
WTKARFQSAA ATAKGPKGAL SPGGFDDSTL PLVDKSLEGE KTGSRDVIPM DALGPDGYST 840
VDRRERRPRG ASSAGEASEK EPLKLDPSRK APPPGPSRPA VRLVDAVGDA KPQPVDSWV 899 |
Gene Ontology | |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |