CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-025180
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Cullin-1 
Protein Synonyms/Alias
  
Gene Name
 Cul1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
410INNNAVTKMAQSSSKubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 699 AA 
Protein Sequence
MSSNRSQNPH GLKQIGLDQI WDDLRAGIQQ VYTRQSMAKS RYMELYTHVY NYCTSVHQSN 60
QARGAGVPPS KSKKGQTPGG AQFVGLELYK RLKEFLKNYL TNLLKDGEDL MDESVLKFYT 120
QQWEDYRFSS KVLNGICAYL NRHWVRRECD EGRKGIYEIY SLALVTWRDC LFRPLNKQVT 180
NAVLKLIEKE RNGETINTRL ISGVVQSYVE LGLNEDDAFA KGPTLTVYKE SFESQFLADT 240
ERFYTRESTE FLQQNPVTEY MKKAEARLLE EQRRVQVYLH ESTQDELARK CEQVLIEKHL 300
EIFHTEFQNL LDADKNEDLG RMYNLVSRIQ DGLGELKKLL ETHIHNQGLA AIEKCGEAAL 360
NDPKMYVQTV LDVHKKYNAL VMSAFNNDAG FVAALDKACG RFINNNAVTK MAQSSSKSPE 420
LLARYCDSLL KKSSKNPEEA ELEDTLNQVM VVFKYIEDKD VFQKFYAKML AKRLVHQNSA 480
SDDAEASMIS KLKQACGFEY TSKLQRMFQD IGVSKDLNEQ FKKHLTNSEP LDLDFSIQVL 540
SSGSWPFQQS CTFALPSELE RSYQRFTAFY ASRHSGRKLT WLYQLSKGEL VTNCFKNRYT 600
LQASTFQMAI LLQYNTEDAY TVQQLTDSTQ IKMDILAQVL QILLKSKLLV LEDENANVDE 660
VELKPDTLIK LYLGYKNKKL RVNINVPMKT EQKQEQETT 699 
Gene Ontology
 GO:0019005; C:SCF ubiquitin ligase complex; IDA:MGI.
 GO:0004842; F:ubiquitin-protein ligase activity; IC:MGI.
 GO:0006915; P:apoptotic process; IMP:MGI.
 GO:0008283; P:cell proliferation; IMP:MGI.
 GO:0009887; P:organ morphogenesis; IMP:MGI.
 GO:0006513; P:protein monoubiquitination; IGI:MGI.
 GO:0006511; P:ubiquitin-dependent protein catabolic process; IC:MGI. 
Interpro
 IPR016158; Cullin_homology.
 IPR001373; Cullin_N.
 IPR016159; Cullin_repeat-like_dom.
 IPR011991; WHTH_DNA-bd_dom. 
Pfam
 PF00888; Cullin 
SMART
 SM00182; CULLIN 
PROSITE
 PS50069; CULLIN_2 
PRINTS