CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-027420
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Co-chaperone GrpE, putative 
Protein Synonyms/Alias
  
Gene Name
 PF11_0258 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Plasmodium falciparum (isolate 3D7) 
NCBI Taxa ID
 36329 
Lysine Modification
Position
Peptide
Type
References
163DNKVLKEKYLSVLAEacetylation[1]
186MKEIETSKLYCISNFacetylation[1]
247FNKYGIDKYNPINEKacetylation[1]
Reference
 [1] Extensive lysine acetylation occurs in evolutionarily conserved metabolic pathways and parasite-specific functions during Plasmodium falciparum intraerythrocytic development.
 Miao J, Lawrence M, Jeffers V, Zhao F, Parker D, Ge Y, Sullivan WJ Jr, Cui L.
 Mol Microbiol. 2013 Aug;89(4):660-75. [PMID: 23796209] 
Functional Description
 Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner (By similarity). 
Sequence Annotation
  
Keyword
 Chaperone; Complete proteome; Mitochondrion; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 301 AA 
Protein Sequence
MRYSTNIIKK GILSRYCSNI YGMQYIPRAR YFLTFCKNEK CNTMLKKYHP FSTSKMSDNA 60
HYKGEDMNKM KNKENKTNKT NKTNEANKAN ETNETNETIE NSASSPTEGK KKKNSLNESE 120
EANEKKEDIN YEDFNKIDLI NEIKKTKRDM EEKMVDNKVL KEKYLSVLAE NENLRNRYMK 180
EIETSKLYCI SNFAKSLLDV ADNLSLAIKN INEESLKTNE EINNIYKGIE MTETILHNIF 240
NKYGIDKYNP INEKFNPQLH EAIFEINDST KEKGTVATVI QHGYKIKDRI LRAAKVGVVK 300
N 301 
Gene Ontology
 GO:0005759; C:mitochondrial matrix; ISS:GeneDB_Pfalciparum.
 GO:0000774; F:adenyl-nucleotide exchange factor activity; IEA:InterPro.
 GO:0051082; F:unfolded protein binding; ISS:GeneDB_Pfalciparum.
 GO:0006457; P:protein folding; IEA:InterPro.
 GO:0030150; P:protein import into mitochondrial matrix; TAS:GeneDB_Pfalciparum. 
Interpro
 IPR000740; GrpE.
 IPR013805; GrpE_coiled_coil.
 IPR009012; GrpE_head. 
Pfam
 PF01025; GrpE 
SMART
  
PROSITE
 PS01071; GRPE 
PRINTS
 PR00773; GRPEPROTEIN.