UniProt Accession

 APOL3_HUMAN; O95236; B1AHI4; B1AHI5; Q5U5N4; Q9BQ82; Q9BQA3 

Genbank Protein ID

 AF070675; AF324238; AF324233; AF324237; AY014904; AF324238; AF324236; AF324237; AY014902; AY014903; AY014905; AF324238; AY014906; AY014907; AF305227; CR456379; Z95114; Z95114; CH471095; BC042918; BC050596 

Genbank Nucleotide ID

 AAC83233.1; AAK26528.1; AAK26528.1; AAK26528.1; AAG50346.1; AAK26529.1; AAK26529.1; AAK26529.1; AAG50344.1; AAG50345.1; AAG50347.1; AAK26527.1; AAG50348.1; AAG50349.1; AAK20213.1; CAG30265.1; CAQ08518.1; CAQ08519.1; EAW60080.1; AAH42918.1; AAH50596.1 

Protein Name

 Apolipoprotein L3 

Protein Synonyms/Alias

 Apolipoprotein L-III; ApoL-III; TNF-inducible protein CG12-1; CG12_1 

Gene Name

 APOL3 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
85	RFTEEATKYFRERVS	ubiquitination	[1]
267	IDRLKVFKEVMRDIT	ubiquitination	[1, 2]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302] 

Functional Description

 May affect the movement of lipids in the cytoplasm or allow the binding of lipids to organelles. 

Sequence Annotation

  

Keyword

 Alternative splicing; Complete proteome; Cytoplasm; Lipid transport; Polymorphism; Reference proteome; Transport. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 402 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0005576; C:extracellular region; IEA:InterPro.
 GO:0008289; F:lipid binding; IEA:InterPro.
 GO:0005319; F:lipid transporter activity; TAS:ProtInc.
 GO:0004871; F:signal transducer activity; IMP:UniProtKB.
 GO:0006954; P:inflammatory response; TAS:ProtInc.
 GO:0042157; P:lipoprotein metabolic process; IEA:InterPro.
 GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; IMP:UniProtKB. 

Interpro

 IPR008405; ApoL. 

Pfam

 PF05461; ApoL 

SMART

  

PROSITE

  

PRINTS