CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-037449
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 MAP1 light chain LC2 
Protein Synonyms/Alias
  
Gene Name
 MAP1A 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
275GGFLKLSKPCCYIFPubiquitination[1]
343INGLLQRKVAELEEEubiquitination[1, 2]
380VFFNVPEKLRLPDASubiquitination[1, 2]
430EPLTLFHKMGVGRLDubiquitination[1, 2]
445MYVLNPVKDSKEMQFubiquitination[1]
456EMQFLMQKWAGNSKAubiquitination[1]
464WAGNSKAKTGIVLPNubiquitination[1]
513PGNAPQNKILEGLEKubiquitination[1, 2]
520KILEGLEKLRHLDFLubiquitination[1]
535RYPVATQKDLASGAVubiquitination[1]
547GAVPTNLKPSKIKQRubiquitination[1, 2]
2922GPMALSSKGSSGAPVubiquitination[1]
2943IPNHCSGKTADLDFFubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 3041 AA 
Protein Sequence
METEAEPARP HGVAMETTPG LGLRSPGAPL AQNPAELLCE AGAAVAAARW DLQKHSLLIV 60
IGDIGTESQL RAVRAHLEQG ILSWNIDLSS FDLNQQLRLF ITRHLAHFSS EVKGQRTLCH 120
QSEILETIIL VNPSADSISS EVHHLLSSSS AYKLLILSGQ SLEPGGDLIL QSGTYSYENF 180
AQVLHNPEIS QLLSNRDPGI QAFLTVSCLG EGDWSHLGLS SSQETLHLRL NPEPTLPTMD 240
GVAEFSEYVS ETVDVPSPFD LLEPPTSGGF LKLSKPCCYI FPGGRGDSAL FAVNGFNILV 300
DGGSDRKSCF WKLVRHLDRI DSVLLTHIGA DNLPGINGLL QRKVAELEEE QSQGSSSYSD 360
WVKNLISPEL GVVFFNVPEK LRLPDASRKA KRSIEEACLT LQHLNRLGIQ AEPLYRVVSN 420
TIEPLTLFHK MGVGRLDMYV LNPVKDSKEM QFLMQKWAGN SKAKTGIVLP NGKEAEISVP 480
YLTSITALVV WLPANPTEKI VRVLFPGNAP QNKILEGLEK LRHLDFLRYP VATQKDLASG 540
AVPTNLKPSK IKQRADSKES LKATTKTAVS KLAKREEVVE EGAKEARSEL AKELAKTEKK 600
AKESSEKPPE KPAKPERVKT ESSEALKAEK RKLIKDKVGK KHLKEKISKL EEKKDKEKKE 660
IKKERKELKK DEGRKEEKKD AKKEEKRKDT KPELKKISKP DLKPFTPEVR KTLYKAKVPG 720
RVKIDRSRAI RGEKELSSEP QTPPAQKGTV PLPTISGHRE LVLSSPEDLT QDFEEMKREE 780
RALLAEQRDT GLGDKPFPLD TAEEGPPSTA IQGTPPSVPG LGQEEHVMKE KELVPEVPEE 840
QGSKDRGLDS GAETEEEKDT WEEKKQREAE RLPDRTEARE ESEPEVKEDV IEKAELEEME 900
EVHPSDEEEE DATKAEGFYQ KHMQEPLKVT PRSREAFGGR ELGLQGKAPE KETSLFLSSL 960
TTPAGATEHV SYIQDETIPG YSETEQTISD EEIHDEPEER PAPPRFHTST YDLPGPEGAG 1020
PFEASQPADS AVPATSGKVY GTPETELTYP TNIVAAPLAE EEHVSSATSI TECDKLSSFA 1080
TSVAEDQSVA SLTAPQTEET GKSSLLLDTV TSIPSSRTEA TQGLDYVPSA GTISPTSSLE 1140
EDKGFKSPPC EDFSVTGESE KRGEIIGKGL SGERAVEEEE EETANVEMSE KLCSQYGTPV 1200
FSAPGHALHP GEPALGEAEE RCLSPDDSTV KMASPPPSGP PSATHTPFHQ SPVEEKSEPQ 1260
DFQEADSWGD TKRTPGVGKE DAAEETVKPG PEEGTLEKEE KVPPPRSPQA QEAPVNIDEG 1320
LTGCTIQLLP AQDKAIVFEI MEAGEPTGPI LGAEALPGGL RTLPQEPGKP QKDEVLRYPD 1380
RSLSPEDAES LSVLSVPSPD TANQEPTPKS PCGLTEQYLH KDRWPEVSPE DTQSLSLSEE 1440
SPSKETSLDV SSKQLSPESL GTLQFGELNL GKEEMGHLMQ AEDTSHHTAP MSVPEPHAAT 1500
ASPPTDGTTR YSAQTDITDD SLDRKSPASS FSHSTPSGNG KYLPGAITSP DEHILTPDSS 1560
FSKSPESLPG PALEDIAIKW EDKVPGLKDR TSEQKKEPEP KDEVLQQKDK TLEHKEVVEP 1620
KDTAIYQKDE ALHVKNEAVK QQDKALEQKG RDLEQKDTAL EQKDKALEPK DKDLEEKDKA 1680
LEQKDKIPEE KDKALEQKDT ALEQKDKALE PKDKDLEQKD RVLEQKEKIP EEKDKALDQK 1740
VRSVEHKAPE DTVAEMKDRD LEQTDKAPEQ KHQAQEQKDK VSEKKDQALE QKYWALGQKD 1800
EALEQNIQAL EENHQTQEQE SLVQEDKTRK PKMLEEKSPE KVKAMEEKLE ALLEKTKALG 1860
LEESLVQEGR AREQEEKYWR GQDVVQEWQE TSPTREEPAG EQKELAPAWE DTSPEQDNRY 1920
WRGREDVALE QDTYWRELSC ERKVWFPHEL DGQGARPHYT EERESTFLDE GPDDEQEVPL 1980
REHATRSPWA SDFKDFQESS PQKGLEVERW LAESPVGLPP EEEDKLTRSP FEIISPPASP 2040
PEMVGQRVPS APGQESPIPD PKLMPHMKNE PTTPSWLADI PPWVPKDRPL PPAPLSPAPG 2100
PPTPAPESHT PAPFSWGTAE YDSVVAAVQE GAAELEGGPY SPLGKDYRKA EGEREEEGRA 2160
EAPDKSSHSS KVPEASKSHA TTEPEQTEPE QREPTPYPDE RSFQYADIYE QMMLTGLGPA 2220
CPTREPPLGA AGDWPPCLST KEAAAGRNTS AEKELSSPIS PKSLQSDTPT FSYAALAGPT 2280
VPPRPEPGPS MEPSLTPPAV PPRAPILSKG PSPPLNGNIL SCSPDRRSPS PKESGRSHWD 2340
DSTSDSELEK GAREQPEKEA QSPSPPHPIP MGSPTLWPET EAHVSPPLDS HLGPARPSLD 2400
FPASAFGFSS LQPAPPQLPS PAEPRSAPCG SLAFSGDRAL ALAPGPPTRT RHDEYLEVTK 2460
APSLDSSLPQ LPSPSSPGAP LLSNLPRPAS PALSEGSSSE ATTPVISSVA ERFSPSLEAA 2520
EQESGELDPG MEPAAHSLWD LTPLSPAPPA SLDLALAPAP SLPGDMGDGI LPCHLECSEA 2580
ATEKPSPFQV PSEDCAANGP TETSPNPPGP APAKAENEEA AACPAWERGA WPEGAERSSR 2640
PDTLLSPEQP VCPAGGSGGP PSSASPEVEA GPQGCATEPR PHRGELSPSF LNPPLPPSID 2700
DRDLSTEEVR LVGRGGRRRV GGPGTTGGPC PVTDETPPTS ASDSGSSQSD SDVPPETEEC 2760
PSITAEAALD SDEDGDFLPV DKAGGVSGTH HPRPGHDPPP LPQPDPRPSP PRPDVCMADP 2820
EGLSSESGRV ERLREKEKVQ GRVGRRAPGK AKPASPARRL DLRGKRSPTP GKGPADRASR 2880
APPRPRSTTS QVTPAEEKDG HSPMSKGLVN GLKAGPMALS SKGSSGAPVY VDLAYIPNHC 2940
SGKTADLDFF RRVRASYYVV SGNDPANGEP SRAVLDALLE GKAQWGENLQ VTLIPTHDTE 3000
VTREWYQQTH EQQQQLNVLV LASSSTVVMQ DESFPACKIE F 3041 
Gene Ontology
 GO:0005874; C:microtubule; IEA:InterPro.
 GO:0016787; F:hydrolase activity; IEA:InterPro.
 GO:0000226; P:microtubule cytoskeleton organization; IEA:InterPro. 
Interpro
 IPR001279; Beta-lactamas-like.
 IPR026074; MAP1.
 IPR015656; MAP1A. 
Pfam
  
SMART
  
PROSITE
  
PRINTS