CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-036809
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Receptor-type tyrosine-protein phosphatase N2 
Protein Synonyms/Alias
  
Gene Name
 PTPRN2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
932NKMAKGAKEIDIAATacetylation[1]
Reference
 [1] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Hydrolase; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 977 AA 
Protein Sequence
MGPPLPLLLL LLLLLPPRVL PAAPSSVPRG RQLPGRLGCL LEEGLCGASE ACVNGFTWQD 60
DYTQYVMDQE LADLPKTYLR RPEASSPARP SKHSVGSERR YSREGGAALA NALRRHLPFL 120
EALSQAPASD VLARTHTAQD RPPAEGDDRF SESILTYVAH TSALTYPPGS RTQLREDLLP 180
RTLGQLQPDE LSPKVDSGVD RHHLMAALSA YAAQRPPAPP GEGSLEPQYL LRAPSRMPRP 240
LLAPAAPQKW PSPLGDSEDP SSTGDGARIH TLLKDLQRQP AEVRGLSGLE LDGMAELMAG 300
LMQGVDHGVA RGSPGRAALG ESGEQADGPK ATLRGDSFPD DGVQDDDDRL YQEVHRLSAT 360
LGGLLQDHGS RLLPGALPFA RPLDMERKKS EHPESSLSSE EETAGVENVK SQTYSKDLLG 420
QQPHSEPGAA AFGELQNQMP GPSKEEQSLP AGAQEALSDG LQLEVQPSEE EARGYIVTDR 480
DPLRPEEGRR LVEDVARLLQ VPSSAFADVE VLGPAVTFKV SANVQNVTTE DVEKATVDNK 540
DKLEETSGLK ILQTGVGSKS KLKFLPPQAE QEDSTKFIAL TLVSLACILG VLLASGLIYC 600
LRHSSQHRLK EKLSGLGGDP GADATAAYQE LCRQRMATRP PDRPEGPHTS RISSVSSQFS 660
DGPIPSPSAR SSASSWSEEP VQSNMDISTG HMILSYMEDH LKNKNRLEKE WEALCAYQAE 720
PNSSFVAQRE ENVPKNRSLA VLTYDHSRVL LKAENSHSHS DYINASPIMD HDPRNPAYIA 780
TQGPLPATVA DFWQMVWESG CVVIVMLTPL AENGVRQCYH YWPDEGSNLY HIYEVNLVSE 840
HIWCEDFLVR SFYLKNLQTN ETRTVTQFHF LSWYDRGVPS SSRSLLDFRR KVNKCYRGRS 900
CPIIVHCSDG AGRSGTYVLI DMVLNKMAKG AKEIDIAATL EHLRDQRPGM VQTKEQFEFA 960
LTAVAEEVNA ILKALPQ 977 
Gene Ontology
 GO:0004725; F:protein tyrosine phosphatase activity; IEA:InterPro.
 GO:0035335; P:peptidyl-tyrosine dephosphorylation; IEA:GOC. 
Interpro
 IPR021613; Receptor_IA-2.
 IPR000387; Tyr/Dual-sp_Pase.
 IPR016130; Tyr_Pase_AS.
 IPR000242; Tyr_Pase_rcpt/non-rcpt. 
Pfam
 PF11548; Receptor_IA-2
 PF00102; Y_phosphatase 
SMART
 SM00194; PTPc 
PROSITE
 PS00383; TYR_PHOSPHATASE_1
 PS50056; TYR_PHOSPHATASE_2
 PS50055; TYR_PHOSPHATASE_PTP 
PRINTS
 PR00700; PRTYPHPHTASE.