CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-009187
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Somatostatin 
Protein Synonyms/Alias
 Antrin; Somatostatin-28; Somatostatin-14 
Gene Name
 Sst 
Gene Synonyms/Alias
 Smst 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
37RLRQFLQKSLAAATGacetylation[1]
45SLAAATGKQELAKYFacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405
Functional Description
 Somatostatin inhibits the release of somatotropin. 
Sequence Annotation
 DISULFID 105 116  
Keyword
 Cleavage on pair of basic residues; Complete proteome; Direct protein sequencing; Disulfide bond; Hormone; Reference proteome; Secreted; Signal. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 116 AA 
Protein Sequence
MLSCRLQCAL AALCIVLALG GVTGAPSDPR LRQFLQKSLA AATGKQELAK YFLAELLSEP 60
NQTENDALEP EDLPQAAEQD EMRLELQRSA NSNPAMAPRE RKAGCKNFFW KTFTSC 116 
Gene Ontology
 GO:0005615; C:extracellular space; IDA:RGD.
 GO:0043025; C:neuronal cell body; IDA:RGD.
 GO:0005179; F:hormone activity; TAS:RGD.
 GO:0006972; P:hyperosmotic response; IEP:RGD.
 GO:0030334; P:regulation of cell migration; IEA:Compara.
 GO:0043200; P:response to amino acid stimulus; IEP:RGD.
 GO:0042493; P:response to drug; IEP:RGD.
 GO:0009408; P:response to heat; IEP:RGD.
 GO:0048545; P:response to steroid hormone stimulus; IEP:RGD. 
Interpro
 IPR004250; Somatostatin.
 IPR018142; Somatostatin/Cortistatin_C. 
Pfam
 PF03002; Somatostatin 
SMART
  
PROSITE
  
PRINTS