CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-025247
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Putative uncharacterized protein 
Protein Synonyms/Alias
  
Gene Name
 Zhx2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
542EKSQGQLKTLEDSFLubiquitination[1]
599LDSMGSGKKGSDAVAubiquitination[1]
664EYDQLAAKTGLVRTEubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 DNA-binding; Homeobox; Nucleus. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 836 AA 
Protein Sequence
MASKRKSTTP CMVRTSQVLE QDMLEEADRA KDKGAGMPQS DVTKDSWAAE PEHSSKETEV 60
VEVKSMGENL SKKLQGGYEC KYCPYSTQNL NEFTEHVDMQ HPNVILNPLY VCAECNFTTK 120
KYDSLSDHNS KFHPGETNFK LKLIKRNNQT VLEQSIEATN HVVPITASGP GSSDNDPGVS 180
VGKTPMTKTG KLKADAKKVP KKPDEAAPEN HMEGTARLVT DTAEILARLG SVELLQDSLG 240
HVMPSVQLPP NINLVPKVPV PLNTTKYNSA LDTNATMINS FNKFPYPTQA ELSWLTAASK 300
HPEEHIRIWF ATQRLKHGIS WSPEEVEEAR KKMFNGTIQS VPPTITVLPA QLTPTKVSQP 360
ILQTALPCQI LGQPSLVLTQ VTSGSTTVSC SPITLAVAGV TNHGQKRPLV TPQAAPEPKR 420
PHIAQVPEPP PKVANTPLTP ASDRKKTKLQ IAHLKASFLQ SQFPDDAEVY RLIEVTGLAR 480
SEIKKWFSDH RYRCQRGIVH ITSESLAKGQ MAITGTRHGR TYHVYPDFAP QKFKEKSQGQ 540
LKTLEDSFLK SSFPTQAEVE RLRVETKLSR REIDSWFSER RKLRDSMEQA VLDSMGSGKK 600
GSDAVAPNGA LSRLDQLSGA QLAGSLPSPS SAIVQNQEQV HLLRSTFART QWPTPQEYDQ 660
LAAKTGLVRT EIVRWFKENR CLLKTGTLSW LEQYQRHHMS DDRGRDAVSR KVAKQVAESP 720
KNGSEAAHQY AKDPKALSEE DSEKLVPRMK VGGDPTKDCL AGKPSEATSD RSEGSRDGQG 780
SEENEESGIV DFVEVTVGEE DAISEKWGSW SRRVAEGTVE RADSDSDSTP AEAGQA 836 
Gene Ontology
 GO:0005634; C:nucleus; IDA:MGI.
 GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
 GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0006402; P:mRNA catabolic process; IDA:MGI.
 GO:0045665; P:negative regulation of neuron differentiation; IDA:MGI.
 GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:MGI.
 GO:0035019; P:somatic stem cell maintenance; IDA:MGI. 
Interpro
 IPR001356; Homeodomain.
 IPR009057; Homeodomain-like.
 IPR007087; Znf_C2H2.
 IPR015880; Znf_C2H2-like. 
Pfam
 PF00046; Homeobox 
SMART
 SM00389; HOX
 SM00355; ZnF_C2H2 
PROSITE
 PS50071; HOMEOBOX_2
 PS50157; ZINC_FINGER_C2H2_2 
PRINTS