UniProt Accession

 NXSC_PSSEM; Q7T2I5; P01435 

Genbank Protein ID

 X51410; AB098530 

Genbank Nucleotide ID

 CAA35770.1; BAC78203.1 

Protein Name

 Erabutoxin c 

Protein Synonyms/Alias

 Short neurotoxin 1c 

Gene Name

 ETXC 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Pseudolaticauda semifasciata (Black-banded sea krait) (Laticaud 

NCBI Taxa ID

 8631 

Lysine Modification

Position	Peptide	Type	References
48	GESSCYHKQWSDFRG	acetylation	[1]
68	GCGCPTVKPGINLSC	acetylation	[1]

Reference

 [1] Molecular conformation and function of erabutoxins as studied by nuclear magnetic resonance.
 Inagaki F, Tamiya N, Miyazawa T.
 Eur J Biochem. 1980 Aug;109(1):129-38. [PMID: 6773770] 

Functional Description

 Produces peripheral paralysis by blocking neuromuscular transmission at the postsynaptic site. Binds to the muscular nicotinic acetylcholine receptor. 

Sequence Annotation

 DISULFID 24 45
 DISULFID 38 62
 DISULFID 64 75
 DISULFID 76 81  

Keyword

 Acetylcholine receptor inhibiting toxin; Direct protein sequencing; Disulfide bond; Ion channel impairing toxin; Neurotoxin; Postsynaptic neurotoxin; Secreted; Signal; Toxin. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 83 AA 

Protein Sequence

Gene Ontology

 GO:0035792; C:other organism postsynaptic membrane; IEA:UniProtKB-KW.
 GO:0035821; P:modification of morphology or physiology of other organism; IEA:InterPro. 

Interpro

 IPR003571; Snake_toxin.
 IPR018354; Snake_toxin_BS. 

Pfam

 PF00087; Toxin_1 

SMART

  

PROSITE

 PS00272; SNAKE_TOXIN 

PRINTS