CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-011897
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Uncharacterized protein KIAA0195 
Protein Synonyms/Alias
 Transmembrane protein 94 
Gene Name
 KIAA0195 
Gene Synonyms/Alias
 TMEM94 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
6**MDLKEKHLGEPPSubiquitination[1]
27RKALSVLKEQLEAVLubiquitination[2]
351RVLAQMSKASPSSLLubiquitination[2]
644IGFTPGAKELFKQENubiquitination[1]
648PGAKELFKQENHLALubiquitination[1]
Reference
 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [2] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983] 
Functional Description
  
Sequence Annotation
 MOD_RES 221 221 Phosphoserine.
 MOD_RES 225 225 Phosphoserine.
 MOD_RES 445 445 Phosphoserine (By similarity).
 MOD_RES 513 513 Phosphoserine.
 CARBOHYD 475 475 N-linked (GlcNAc...) (Potential).
 CARBOHYD 516 516 N-linked (GlcNAc...) (Potential).
 CARBOHYD 1202 1202 N-linked (GlcNAc...) (Potential).
 CARBOHYD 1205 1205 N-linked (GlcNAc...) (Potential).  
Keyword
 Alternative splicing; Complete proteome; Glycoprotein; Membrane; Phosphoprotein; Polymorphism; Reference proteome; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1356 AA 
Protein Sequence
MDLKEKHLGE PPSALGLSTR KALSVLKEQL EAVLEGHLRE RKKCLTWKEV WRSSFLHHSN 60
RCSCFHWPGA SLMLLAVLLL LGCCGGQPAG SRGVGLVNAS ALFLLLLLNL VLIGRQDRLK 120
RREVERRLRG IIDQIQDALR DGREIQWPSA MYPDLHMPFA PSWSLHWAYR DGHLVNLPVS 180
LLVEGDIIAL RPGQESFASL RGIKDDEHIV LEPGDLFPPF SPPPSPRGEV ERGPQSPQQH 240
RLFRVLETPV IDNIRWCLDM ALSRPVTALD NERFTVQSVM LHYAVPVVLA GFLITNALRF 300
IFSAPGVTSW QYTLLQLQVN GVLPILPLLF PVLWVLATAC GEARVLAQMS KASPSSLLAK 360
FSEDTLSSYT EAVSSQEMLR CIWGHFLRVL GGTSPTLSHS SSLLHSLGSV TVLCCVDKQG 420
ILSWPNPSPE TVLFFSGKVE PPHSSHEDLT DGLSTRSFCH PEPHERDALL AGSLNNTLHL 480
SNEQERGDWP GEAPKPPEPY SHHKAHGRSK HPSGSNVSFS RDTEGGEEEP SKTQPGMESD 540
PYEAEDFVCD YHLEMLSLSQ DQQNPSCIQF DDSNWQLHLT SLKPLGLNVL LNLCDASVTE 600
RLCRFSDHLC NIALQESHSA VLPVHVPWGL CELARLIGFT PGAKELFKQE NHLALYRLPS 660
AETMKETSLG RLSCVTKRRP PLSHMISLFI KDTTTSTEQM LSHGTADVVL EACTDFWDGA 720
DIYPLSGSDR KKVLDFYQRA CLSGYCSAFA YKPMNCALSS QLNGKCIELV QVPGQSSIFT 780
MCELPSTIPI KQNARRSSWS SDEGIGEVLE KEDCMQALSG QIFMGMVSSQ YQARLDIVRL 840
IDGLVNACIR FVYFSLEDEL KSKVFAEKMG LETGWNCHIS LTPNGDMPGS EIPPSSPSHA 900
GSLHDDLNQV SRDDAEGLLL MEEEGHSDLI SFQPTDSDIP SFLEDSNRAK LPRGIHQVRP 960
HLQNIDNVPL LVPLFTDCTP ETMCEMIKIM QEYGEVTCCL GSSANLRNSC LFLQSDISIA 1020
LDPLYPSRCS WETFGYATSI SMAQASDGLS PLQLSGQLNS LPCSLTFRQE ETISIIRLIE 1080
QARHATYGIR KCFLFLLQCQ LTLVVIQFLS CLVQLPPLLS TTDILWLSCF CYPLLSISLL 1140
GKPPHSSIMS MATGKNLQSI PKKTQHYFLL CFLLKFSLTI SSCLICFGFT LQSFCDSSRD 1200
RNLTNCSSVM LPSNDDRAPA WFEDFANGLL SAQKLTAALI VLHTVFISIT HVHRTKPLWR 1260
KSPLTNLWWA VTVPVVLLGQ VVQTAVDLQL WTHRDSHVHF GLEDVPLLTW LLGCLSLVLV 1320
VVTNEIVKLH EIRVRVRYQK RQKLQFETKL GMNSPF 1356 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. 
Interpro
 IPR006068; ATPase_P-typ_cation-transptr_C.
 IPR023298; ATPase_P-typ_TM_dom. 
Pfam
 PF00689; Cation_ATPase_C 
SMART
  
PROSITE
  
PRINTS