CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-030714
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Breast cancer type 1 susceptibility protein 
Protein Synonyms/Alias
 cDNA FLJ58524, highly similar to Homo sapiens breast cancer 1, early onset (BRCA1), transcript variant BRCA1-delta 11b, mRNA 
Gene Name
 BRCA1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
516EEFMLVYKFARKHHIubiquitination[1]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 712 AA 
Protein Sequence
MLKLLNQKKG PSQCPLCKND ITKRSLQEST RFSQLVEELL KIICAFQLDT GLEYANSYNF 60
AKKENNSPEH LKDEVSIIQS MGYRNRAKRL LQSEPENPSL QETSLSVQLS NLGTVRTLRT 120
KQRIQPQKTS VYIELGSDSS EDTVNKATYC SVGDQELLQI TPQGTRDEIS LDSAKKAACE 180
FSETDVTNTE HHQPSNNDLN TTEKRAAERH PEKYQGEAAS GCESETSVSE DCSGLSSQSD 240
ILTTQQRDTM QHNLIKLQQE MAELEAVLEQ HGSQPSNSYP SIISDSSALE DLRNPEQSTS 300
EKVLTSQKSS EYPISQNPEG LSADKFEVSA DSSTSKNKEP GVERSSPSKC PSLDDRWYMH 360
SCSGSLQNRN YPSQEELIKV VDVEEQQLEE SGPHDLTETS YLPRQDLEGT PYLESGISLF 420
SDDPESDPSE DRAPESARVG NIPSSTSALK VPQLKVAESA QSPAAAHTTD TAGYNAMEES 480
VSREKPELTA STERVNKRMS MVVSGLTPEE FMLVYKFARK HHITLTNLIT EETTHVVMKT 540
DAEFVCERTL KYFLGIAGGK WVVSYFWVTQ SIKERKMLNE HDFEVRGDVV NGRNHQGPKR 600
ARESQDRKIF RGLEICCYGP FTNMPTDQLE WMVQLCGASV VKELSSFTLG TGVHPIVVVQ 660
PDAWTEDNGF HAIGQMCEAP VVTREWVLDS VALYQCQELD TYLIPQIPHS HY 712 
Gene Ontology
 GO:0005634; C:nucleus; IEA:InterPro.
 GO:0003677; F:DNA binding; IEA:InterPro.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0006281; P:DNA repair; IEA:InterPro. 
Interpro
 IPR011364; BRCA1.
 IPR001357; BRCT_dom. 
Pfam
 PF00533; BRCT 
SMART
 SM00292; BRCT 
PROSITE
 PS50172; BRCT 
PRINTS