CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-011699
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 PI-PLC X domain-containing protein 2 
Protein Synonyms/Alias
  
Gene Name
 PLCXD2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
79PDQTQAIKRLARISLubiquitination[1]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983] 
Functional Description
  
Sequence Annotation
 DOMAIN 42 215 PI-PLC X-box.
 ACT_SITE 57 57 By similarity.
 ACT_SITE 132 132 By similarity.  
Keyword
 Alternative splicing; Complete proteome; Hydrolase; Lipid degradation; Lipid metabolism; Reference proteome; Transducer. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 305 AA 
Protein Sequence
MLAVRKARRK LRMGTICSPN PSGTKTSSEV CNADWMASLP PHLHNLPLSN LAIPGSHDSF 60
SYWVDEKSPV GPDQTQAIKR LARISLVKKL MKKWSVTQNL TFREQLEAGI RYFDLRVSSK 120
PGDADQEIYF IHGLFGIKVW DGLMEIDSFL TQHPQEIIFL DFNHFYAMDE THHKCLVLRI 180
QEAFGNKLCP ACSVESLTLR TLWEKNCQVL IFYHCPFYKQ YPFLWPGKKI PAPWANTTSV 240
RKLILFLETT LSERASRGSF HVSQAILTPR VKTIARGLVG GLKNTLVHSN RWNSHGPSLL 300
SQERS 305 
Gene Ontology
 GO:0008081; F:phosphoric diester hydrolase activity; IEA:InterPro.
 GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
 GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW. 
Interpro
 IPR017946; PLC-like_Pdiesterase_TIM-brl.
 IPR000909; PLipase_C_PInositol-sp_X_dom. 
Pfam
 PF00388; PI-PLC-X 
SMART
  
PROSITE
 PS50007; PIPLC_X_DOMAIN 
PRINTS