UniProt Accession

 Q3UT49_MOUSE; Q3UT49 

Genbank Protein ID

 AC120840; AC139233; AK139760 

Genbank Nucleotide ID

 BAE24131.1 

Protein Name

 Cytochrome P450 2C29 

Protein Synonyms/Alias

  

Gene Name

 Cyp2c29 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
69	PMAEKIIKGFGVVFS	ubiquitination	[1]
153	NRFDYKDKEFLILMD	acetylation	[2]
153	NRFDYKDKEFLILMD	ubiquitination	[1]
161	EFLILMDKINENVKI	ubiquitination	[1]
196	GSHHKIVKNFNYLKS	acetylation	[3]
196	GSHHKIVKNFNYLKS	ubiquitination	[1]
202	VKNFNYLKSYLLEKI	acetylation	[3]
202	VKNFNYLKSYLLEKI	ubiquitination	[1]
208	LKSYLLEKIKEHKES	ubiquitination	[1]
210	SYLLEKIKEHKESLD	acetylation	[3]
213	LEKIKEHKESLDVTN	acetylation	[2, 3]
213	LEKIKEHKESLDVTN	ubiquitination	[1]
283	KYPDVTAKVQEEIDR	ubiquitination	[1]
336	HAVTCDIKFRKYLIP	acetylation	[2, 3]
336	HAVTCDIKFRKYLIP	ubiquitination	[1]
339	TCDIKFRKYLIPKGT	acetylation	[3]
344	FRKYLIPKGTTVITS	ubiquitination	[1]
381	LNGNGNFKKSDYFMP	ubiquitination	[1]
382	NGNGNFKKSDYFMPF	ubiquitination	[1]
393	FMPFSTGKRICAGEG	acetylation	[2]
393	FMPFSTGKRICAGEG	ubiquitination	[1]

Reference

 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023]
 [2] Quantification of mitochondrial acetylation dynamics highlights prominent sites of metabolic regulation.
 Still AJ, Floyd BJ, Hebert AS, Bingman CA, Carson JJ, Gunderson DR, Dolan BK, Grimsrud PA, Dittenhafer-Reed KE, Stapleton DS, Keller MP, Westphall MS, Denu JM, Attie AD, Coon JJ, Pagliarini DJ.
 J Biol Chem. 2013 Jul 17;. [PMID: 23864654]
 [3] Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways.
 Rardin MJ, Newman JC, Held JM, Cusack MP, Sorensen DJ, Li B, Schilling B, Mooney SD, Kahn CR, Verdin E, Gibson BW.
 Proc Natl Acad Sci U S A. 2013 Apr 16;110(16):6601-6. [PMID: 23576753] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Heme; Iron; Metal-binding; Monooxygenase; Oxidoreductase; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 451 AA 

Protein Sequence

Gene Ontology

 GO:0009055; F:electron carrier activity; IEA:InterPro.
 GO:0020037; F:heme binding; IEA:InterPro.
 GO:0005506; F:iron ion binding; IEA:InterPro.
 GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.
 GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. 

Interpro

 IPR001128; Cyt_P450.
 IPR017972; Cyt_P450_CS.
 IPR002401; Cyt_P450_E_grp-I. 

Pfam

 PF00067; p450 

SMART

  

PROSITE

 PS00086; CYTOCHROME_P450 

PRINTS

 PR00463; EP450I.
 PR00385; P450.