CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-007158
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 DUP240 protein YAR028W 
Protein Synonyms/Alias
  
Gene Name
 YAR028W; FUN56 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
188QSPVSAGKTSNGLNNubiquitination[1]
217LKATQIEKEAQSEYWubiquitination[1, 2, 3, 4, 5]
226AQSEYWRKQYPDADLubiquitination[1]
Reference
 [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, VillĂ©n J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301]
 [2] A subset of membrane-associated proteins is ubiquitinated in response to mutations in the endoplasmic reticulum degradation machinery.
 Hitchcock AL, Auld K, Gygi SP, Silver PA.
 Proc Natl Acad Sci U S A. 2003 Oct 28;100(22):12735-40. [PMID: 14557538]
 [3] Computational identification of ubiquitylation sites from protein sequences.
 Tung CW, Ho SY.
 BMC Bioinformatics. 2008 Jul 15;9:310. [PMID: 18625080]
 [4] Identification, analysis, and prediction of protein ubiquitination sites.
 Radivojac P, Vacic V, Haynes C, Cocklin RR, Mohan A, Heyen JW, Goebl MG, Iakoucheva LM.
 Proteins. 2010 Feb 1;78(2):365-80. [PMID: 19722269]
 [5] Sites of ubiquitin attachment in Saccharomyces cerevisiae.
 Starita LM, Lo RS, Eng JK, von Haller PD, Fields S.
 Proteomics. 2012 Jan;12(2):236-40. [PMID: 22106047
Functional Description
  
Sequence Annotation
 CROSSLNK 217 217 Glycyl lysine isopeptide (Lys-Gly)  
Keyword
 Complete proteome; Isopeptide bond; Membrane; Reference proteome; Transmembrane; Transmembrane helix; Ubl conjugation. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 234 AA 
Protein Sequence
MQTPSENTDV KMDTLDEPSA HLIEENVALP EDTFSSHLSY VLYEIAHCKP IMFMIIIIVS 60
LISLIVLFHD NDGCTVILVM SLIVASMALM VVAAFTFGKA ITEQEFMIKL LVEVIARKPA 120
GKEWGTVAYN MNQYLFMKRL WYTPYYFYSG KKCHEFFTTL IKEVNSGSHS DSSSNSAEDT 180
QSPVSAGKTS NGLNNFYSIR SDPILMAYVL KATQIEKEAQ SEYWRKQYPD ADLP 234 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. 
Interpro
 IPR001142; DUP. 
Pfam
 PF00674; DUP 
SMART
  
PROSITE
  
PRINTS