UniProt Accession

 D3YYK0_MOUSE; D3YYK0 

Genbank Protein ID

 AC084109; CH466529 

Genbank Nucleotide ID

 EDL19400.1 

Protein Name

 Abhydrolase domain containing 11, isoform CRA_b 

Protein Synonyms/Alias

 Alpha/beta hydrolase domain-containing protein 11 

Gene Name

 Abhd11 

Gene Synonyms/Alias

 mCG_16705 

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
116	QARKLADKQLSSVVK	acetylation	[1, 2]
116	QARKLADKQLSSVVK	succinylation	[2]
123	KQLSSVVKEAGIRQF	acetylation	[3]

Reference

 [1] Proteomic investigations of lysine acetylation identify diverse substrates of mitochondrial deacetylase sirt3.
 Sol EM, Wagner SA, Weinert BT, Kumar A, Kim HS, Deng CX, Choudhary C.
 PLoS One. 2012;7(12):e50545. [PMID: 23236377]
 [2] SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways.
 Park J, Chen Y, Tishkoff DX, Peng C, Tan M, Dai L, Xie Z, Zhang Y, Zwaans BM, Skinner ME, Lombard DB, Zhao Y.
 Mol Cell. 2013 Jun 27;50(6):919-30. [PMID: 23806337]
 [3] Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways.
 Rardin MJ, Newman JC, Held JM, Cusack MP, Sorensen DJ, Li B, Schilling B, Mooney SD, Kahn CR, Verdin E, Gibson BW.
 Proc Natl Acad Sci U S A. 2013 Apr 16;110(16):6601-6. [PMID: 23576753] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Hydrolase; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 227 AA 

Protein Sequence

Gene Ontology

 GO:0005739; C:mitochondrion; IDA:MGI.
 GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
 GO:0008152; P:metabolic process; IEA:GOC. 

Interpro

 IPR000073; AB_hydrolase_1.
 IPR000639; Epox_hydrolase-like. 

Pfam

  

SMART

  

PROSITE

  

PRINTS

 PR00111; ABHYDROLASE.
 PR00412; EPOXHYDRLASE.