CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-028337
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Centromere/kinetochore protein zw10 homolog 
Protein Synonyms/Alias
 ZW10 protein 
Gene Name
 ZW10 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
17AHSGRLEKEDLGTRIubiquitination[1]
74SEDIDLLKSRIESEVubiquitination[1, 2]
96TGEFTDLKQQLERDSubiquitination[1, 2]
130NCALTEKKYVTGAQRubiquitination[1]
143QRLEEAQKCLKLLKSubiquitination[1]
382LKEMRFLKGDTTDLLubiquitination[1, 3]
390GDTTDLLKYARNINSubiquitination[1]
403NSHFANKKCQDVIVAubiquitination[1]
597LAQMRAQKGELLERLubiquitination[1]
624ENYSAASKAVRQVLHubiquitination[1, 2]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [3] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 672 AA 
Protein Sequence
MASFVTEVLA HSGRLEKEDL GTRISRLTRR VEEIKGEVCN MISKKYSEFL PSMQSAQGLI 60
TQVDKLSEDI DLLKSRIESE VRRDLHVSTG EFTDLKQQLE RDSVVLSLLK QLQEFSTAIE 120
EYNCALTEKK YVTGAQRLEE AQKCLKLLKS RKCFDLKILK SLSMELTIQK QNILYHLGEE 180
WQKLIVWKFP PSKDTSSLES YLQTELHLYT EQSHKEEKTP MPPISSVLLA FSVLGELHSK 240
LKSFGQMLLK YILRPLASCP SLHAVIESQP NIVIIRFESI MTNLEYPSPS EVFTKIRLVL 300
EVLQKQLLDL PLDTDLENEK TSTVPLAEML GDMIWEDLSE CLIKNCLVYS IPTNSSKLQQ 360
YEEIIQSTEE FENALKEMRF LKGDTTDLLK YARNINSHFA NKKCQDVIVA ARNLMTSEIH 420
NTVKIIPDSK INVPELPTPD EDNKLEVQKV SNTQYHEVMN LEPENTLDQH SFSLPTCRIS 480
ESVKKLMELA YQTLLEATTS SDQCAVQLFY SVRNIFHLFH DVVPTYHKEN LQKLPQLAAI 540
HHNNCMYIAH HLLTLGHQFR LRLAPILCDG TATFVDLVPG FRRLGTECFL AQMRAQKGEL 600
LERLSSARNF SNMDDEENYS AASKAVRQVL HQLKRLGIVW QDVLPVNIYC KAMGTLLNTA 660
ISEVIGKITA LE 672 
Gene Ontology
 GO:0000775; C:chromosome, centromeric region; IEA:InterPro.
 GO:0005634; C:nucleus; IEA:InterPro.
 GO:0007067; P:mitosis; IEA:InterPro. 
Interpro
 IPR009361; RZZ-complex_Zw10. 
Pfam
 PF06248; Zw10 
SMART
  
PROSITE
  
PRINTS