CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-010280
UniProt Accession
Genbank Protein ID
 U00096 
Genbank Nucleotide ID
Protein Name
 Putative prophage CPZ-55 integrase 
Protein Synonyms/Alias
  
Gene Name
 intZ 
Gene Synonyms/Alias
 b2442 
Created Date
 July 27, 2013 
Organism
 Escherichia coli (strain K12) 
NCBI Taxa ID
 83333 
Lysine Modification
Position
Peptide
Type
References
19DAAQPQDKPYKLTDSacetylation[1]
22QPQDKPYKLTDSLTPacetylation[1]
134QVRSALEKDVYPVLGacetylation[1]
375YNQAAYLKQRRAMMQacetylation[1]
Reference
 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618] 
Functional Description
 Integrase is necessary for integration of the phage into the host genome by site-specific recombination. In conjunction with excisionase, integrase is also necessary for excision of the prophage from the host genome. 
Sequence Annotation
 ACT_SITE 368 368 O-(3'-phospho-DNA)-tyrosine intermediate  
Keyword
 Complete proteome; DNA integration; DNA recombination; Reference proteome; Viral genome integration; Virus entry into host cell. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 402 AA 
Protein Sequence
MSKTPLTAKA IDAAQPQDKP YKLTDSLTPG LFLLVHPNGS KYWRFRYWLN KREFLQAIGV 60
YPLITLKEAR RRATESRSLI ANGINPVEQA RKEKAIDALN MAAGFKKVAE DWFATRVGGW 120
SESYAKQVRS ALEKDVYPVL GKRSIVDITA RDVLALLQKK ERTAPEQARK LRRRIGEIFK 180
FAVITELVTR NPVADLDTAL KARRPGHNAW IPISEIPAFY KALERAGSVQ IQTAIRLLIL 240
TALRTAELRL CRWEWINLED ATITLPAEVM KARRPHVVPL SRQAVELLQD QFTRSGYSAF 300
VFPGRFMDKP LSASAILKAL ERIGYKSIAT GHGWRTTFST ALNESGRYSP DWIEIQLAHV 360
PKGIRGVYNQ AAYLKQRRAM MQDYADAIDS ILAGNGNPLE PE 402 
Gene Ontology
 GO:0003677; F:DNA binding; IEA:InterPro.
 GO:0015074; P:DNA integration; IEA:UniProtKB-KW.
 GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
 GO:0075713; P:establishment of integrated proviral latency; IEA:UniProtKB-KW.
 GO:0046718; P:viral entry into host cell; IEA:UniProtKB-KW. 
Interpro
 IPR011010; DNA_brk_join_enz.
 IPR025166; DUF4102.
 IPR013762; Integrase-like_cat-core.
 IPR002104; Integrase_catalytic.
 IPR023109; Integrase_recombinase_N. 
Pfam
 PF13356; DUF4102
 PF00589; Phage_integrase 
SMART
  
PROSITE
  
PRINTS