CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-003276
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 NAD(P) transhydrogenase subunit beta 
Protein Synonyms/Alias
 Nicotinamide nucleotide transhydrogenase subunit beta; Pyridine nucleotide transhydrogenase subunit beta 
Gene Name
 pntB 
Gene Synonyms/Alias
 b1602; JW1594 
Created Date
 July 27, 2013 
Organism
 Escherichia coli (strain K12) 
NCBI Taxa ID
 83333 
Lysine Modification
Position
Peptide
Type
References
153LCGKISSKPLMLPNRacetylation[1]
332PVAEITEKLRARGINacetylation[1]
416MPVLEVWKAQNVIVFacetylation[1]
424AQNVIVFKRSMNTGYacetylation[1]
441VQNPLFFKENTHMLFacetylation[1]
452HMLFGDAKASVDAILacetylation[1]
460ASVDAILKAL*****acetylation[1]
Reference
 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618] 
Functional Description
 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane. 
Sequence Annotation
  
Keyword
 3D-structure; Cell inner membrane; Cell membrane; Complete proteome; Direct protein sequencing; Membrane; NAD; NADP; Oxidoreductase; Reference proteome; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 462 AA 
Protein Sequence
MSGGLVTAAY IVAAILFIFS LAGLSKHETS RQGNNFGIAG MAIALIATIF GPDTGNVGWI 60
LLAMVIGGAI GIRLAKKVEM TEMPELVAIL HSFVGLAAVL VGFNSYLHHD AGMAPILVNI 120
HLTEVFLGIF IGAVTFTGSV VAFGKLCGKI SSKPLMLPNR HKMNLAALVV SFLLLIVFVR 180
TDSVGLQVLA LLIMTAIALV FGWHLVASIG GADMPVVVSM LNSYSGWAAA AAGFMLSNDL 240
LIVTGALVGS SGAILSYIMC KAMNRSFISV IAGGFGTDGS STGDDQEVGE HREITAEETA 300
ELLKNSHSVI ITPGYGMAVA QAQYPVAEIT EKLRARGINV RFGIHPVAGR LPGHMNVLLA 360
EAKVPYDIVL EMDEINDDFA DTDTVLVIGA NDTVNPAAQD DPKSPIAGMP VLEVWKAQNV 420
IVFKRSMNTG YAGVQNPLFF KENTHMLFGD AKASVDAILK AL 462 
Gene Ontology
 GO:0005887; C:integral to plasma membrane; IDA:EcoCyc.
 GO:0008750; F:NAD(P)+ transhydrogenase (AB-specific) activity; IDA:EcoCyc.
 GO:0050661; F:NADP binding; IDA:EcoCyc.
 GO:0006740; P:NADPH regeneration; IMP:EcoCyc. 
Interpro
 IPR012136; NADH_DH_b. 
Pfam
 PF02233; PNTB 
SMART
  
PROSITE
  
PRINTS