CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-035090
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Protein Akr1c12 
Protein Synonyms/Alias
  
Gene Name
 Akr1c13 
Gene Synonyms/Alias
 Akr1c12 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
25ALGFGTYKPKEVPKSacetylation[1]
273VPLAQSFKENEMRENacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
 ACT_SITE 55 55 Proton donor (By similarity).  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 323 AA 
Protein Sequence
MSSKQHCVKL NDGHFIPALG FGTYKPKEVP KSKSLEAAHL AIDAGYRHID TAYAYQIEEE 60
IGQAIQSKIK AGVVKREDMF ITTKLWCTCF RPELVKPALE KSLKNLQLDY ADLYIMHYPV 120
PMKSGDNDFP VDEKGKSLLD TVDFCDTWEM LEKCKDAGLV KSIGVSNFNH KQLERLLNKP 180
GLKYKPVCNQ VECHLYLNQS KLLDYCKSKD IVLVAYGALG TQRYKEWVDQ NSPVLLNDPV 240
LCDVAKKNKR SPALIALRYL VQRGVVPLAQ SFKENEMREN LQVFDFQLSP EDMKTLDGLN 300
KNFRYLSAEF LAGHPEYPFS EEY 323 
Gene Ontology
 GO:0016491; F:oxidoreductase activity; IEA:InterPro. 
Interpro
 IPR001395; Aldo/ket_red.
 IPR018170; Aldo/ket_reductase_CS.
 IPR020471; Aldo/keto_reductase_subgr.
 IPR023210; NADP_OxRdtase_dom. 
Pfam
 PF00248; Aldo_ket_red 
SMART
  
PROSITE
 PS00798; ALDOKETO_REDUCTASE_1
 PS00062; ALDOKETO_REDUCTASE_2 
PRINTS
 PR00069; ALDKETRDTASE.