Tag | Content |
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CPLM ID | CPLM-025343 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Proteasome subunit alpha type |
Protein Synonyms/Alias | |
Gene Name | Psma4 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
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54 | AERRNIHKLLDEVFF | ubiquitination | [1] | 64 | DEVFFSEKIYKLNED | ubiquitination | [1] | 176 | AAAVSMLKQDYKEGE | ubiquitination | [1] | 199 | LAVKVLNKTMDVSKL | ubiquitination | [1] | 205 | NKTMDVSKLSAEKVE | ubiquitination | [1] | 210 | VSKLSAEKVEIATLT | ubiquitination | [1] | 231 | VIRVLKQKEVEQLIK | ubiquitination | [1] |
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Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity (By similarity). |
Sequence Annotation | |
Keyword | Cytoplasm; Hydrolase; Nucleus; Protease; Proteasome; Threonine protease. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 261 AA |
Protein Sequence | MSRRYDSRTT IFSPEGRLYQ VEYAMEAIGH AGTCLGILAN DGVLLAAERR NIHKLLDEVF 60 FSEKIYKLNE DLACSVAGIT SDANVLTNEL RLIAQRYLLQ YQEPIPCEQL VTALCDIKQA 120 YTQFGGKRPF GVSLLYIGWD KHYGFQLYQS DPSGNYGGWK ATCIGNNSAA AVSMLKQDYK 180 EGEMTLKSAL ALAVKVLNKT MDVSKLSAEK VEIATLTRES GKTVIRVLKQ KEVEQLIKKH 240 EEEEAKAERE KKEKEQREKD K 261 |
Gene Ontology | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:InterPro. GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW. GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |