CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-019943
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 CDK5 regulatory subunit-associated protein 3 
Protein Synonyms/Alias
  
Gene Name
 Cdk5rap3 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
83KGTEASTKNIFGRYSubiquitination[1]
135SLKKQIAKCQQLQQEubiquitination[1]
166EQFYHSCKQYGITGDubiquitination[1]
447QSQLLALKKELMVEKubiquitination[1]
475KLDLLLEKTRELQKLubiquitination[1]
489LIEADISKRYSGRPVubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
 Potential regulator of CDK5 activity. May be involved in cell proliferation. Regulates CDK5 activity via its interaction with CDK5R1 (By similarity). 
Sequence Annotation
  
Keyword
 Complete proteome; Phosphoprotein; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 503 AA 
Protein Sequence
MQDHQHVPID IQTSKLLDWL VDRRHCNLKW QSLVLTIREK INTAIQDMPE SQEIAQLLSG 60
SYIHYFHCLR IVDLLKGTEA STKNIFGRYS SQRMKDWQEI VSLYEKDNTY LVELCSLLVR 120
NVSYEIPSLK KQIAKCQQLQ QEYSRKEEEG QAGAAEMREQ FYHSCKQYGI TGDNVRRELL 180
ALVKDLPSQL AEIGAGAQSL GEAIDLYQAC VEFVCDSPTE QVLPMLRYVQ KKGNSTVYEW 240
RTGTEPSVVE RPQLEEPPEQ VQEDEIDWGD FGVEAVSDSG IVAETPGIDW GISLESEAKD 300
AGADKIDWGD DAAAASEITV LETGTEAPEG VARGSDALTL LEYPETRNQF IDELMELEIF 360
LSQRAVEMSE EADILSVSQF QLAPAILQGQ TKEKMLSLVS TLQQLIGRLT SLRMQHLFMI 420
LASPRYVDRV TEFLQQKLKQ SQLLALKKEL MVEKQQEALQ EQAALEPKLD LLLEKTRELQ 480
KLIEADISKR YSGRPVNLMG TSL 503 
Gene Ontology
 GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IGI:MGI.
 GO:0000079; P:regulation of cyclin-dependent protein serine/threonine kinase activity; ISS:UniProtKB. 
Interpro
 IPR008491; DUF773. 
Pfam
 PF05600; DUF773 
SMART
  
PROSITE
  
PRINTS