UniProt Accession

 CCW12_YEAST; Q12127; D6VYB0 

Genbank Protein ID

 Z73282; U53878; AY557929; BK006945 

Genbank Nucleotide ID

 CAA97677.1; AAB67555.1; AAS56255.1; DAA09426.1 

Protein Name

 Covalently-linked cell wall protein 12 

Protein Synonyms/Alias

 Protein Alpha0.6 

Gene Name

 CCW12 

Gene Synonyms/Alias

 YLR110C; L9354.7 

Created Date

 July 27, 2013 

Organism

 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 

NCBI Taxa ID

 559292 

Lysine Modification

Position	Peptide	Type	References
80	PLTTEAPKNGTSTAA	ubiquitination	[1]

Reference

 [1] Sites of ubiquitin attachment in Saccharomyces cerevisiae.
 Starita LM, Lo RS, Eng JK, von Haller PD, Fields S.
 Proteomics. 2012 Jan;12(2):236-40. [PMID: 22106047] 

Functional Description

 Component of the cell wall. May play a role in the formation of a tightly packed outer mannan layer, which protects the inner glucan. 

Sequence Annotation

 REPEAT 75 88 1.
 REPEAT 91 103 2.
 LIPID 112 112 GPI-anchor amidated glycine (Potential).
 CARBOHYD 21 21 N-linked (GlcNAc...).
 CARBOHYD 23 23 O-linked (Man).
 CARBOHYD 24 24 O-linked (Man).
 CARBOHYD 26 26 O-linked (Man).
 CARBOHYD 28 28 O-linked (Man).
 CARBOHYD 31 31 O-linked (Man).
 CARBOHYD 32 32 O-linked (Man).
 CARBOHYD 33 33 O-linked (Man).
 CARBOHYD 36 36 O-linked (Man).
 CARBOHYD 38 38 O-linked (Man).
 CARBOHYD 39 39 O-linked (Man).
 CARBOHYD 46 46 O-linked (Man).
 CARBOHYD 48 48 O-linked (Man).
 CARBOHYD 81 81 N-linked (GlcNAc...).
 CARBOHYD 97 97 N-linked (GlcNAc...).  

Keyword

 Cell wall; Cell wall biogenesis/degradation; Complete proteome; Direct protein sequencing; Glycoprotein; GPI-anchor; Lipoprotein; Membrane; Reference proteome; Repeat; Secreted; Signal. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 133 AA 

Protein Sequence

Gene Ontology

 GO:0031225; C:anchored to membrane; IEA:UniProtKB-KW.
 GO:0005934; C:cellular bud tip; IDA:SGD.
 GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
 GO:0009277; C:fungal-type cell wall; IDA:SGD.
 GO:0043332; C:mating projection tip; IDA:SGD.
 GO:0000752; P:agglutination involved in conjugation with cellular fusion; IMP:SGD.
 GO:0031505; P:fungal-type cell wall organization; IMP:SGD. 

Interpro

 IPR025928; Flocculin_t3_rpt. 

Pfam

 PF13928; Flocculin_t3 

SMART

  

PROSITE

  

PRINTS