UniProt Accession

 B4DWA6_HUMAN; B4DWA6 

Genbank Protein ID

 AK301442 

Genbank Nucleotide ID

 BAG62968.1 

Protein Name

 cDNA FLJ60094, highly similar to F-actin capping protein subunit beta 

Protein Synonyms/Alias

  

Gene Name

  

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
141	YRSPWSNKYDPPLED	ubiquitination	[1, 2]
158	MPSARLRKLEVEANN	ubiquitination	[1, 2]
298	LNEIYFGKTKDIVNG	ubiquitination	[2]
300	EIYFGKTKDIVNGLR	ubiquitination	[1]
315	SVQTFADKSKQEALK	ubiquitination	[2, 3]
322	KSKQEALKNDLVEAL	ubiquitination	[1]

Reference

 [1] Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass.
 Povlsen LK, Beli P, Wagner SA, Poulsen SL, Sylvestersen KB, Poulsen JW, Nielsen ML, Bekker-Jensen S, Mailand N, Choudhary C.
 Nat Cell Biol. 2012 Oct;14(10):1089-98. [PMID: 23000965]
 [2] hCKSAAP_UbSite: improved prediction of human ubiquitination sites by exploiting amino acid pattern and properties.
 Chen Z, Zhou Y, Song J, Zhang Z.
 Biochim Biophys Acta. 2013 Aug;1834(8):1461-7. [PMID: 23603789]
 [3] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983] 

Functional Description

  

Sequence Annotation

  

Keyword

  

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 335 AA 

Protein Sequence

Gene Ontology

 GO:0008290; C:F-actin capping protein complex; IEA:InterPro.
 GO:0071203; C:WASH complex; IEA:InterPro.
 GO:0030036; P:actin cytoskeleton organization; IEA:InterPro. 

Interpro

 IPR019771; F-actin_capping_bsu_CS.
 IPR001698; WASH_F-actin_cap_beta. 

Pfam

 PF01115; F_actin_cap_B 

SMART

  

PROSITE

 PS00231; F_ACTIN_CAPPING_BETA 

PRINTS

 PR00192; FACTINCAPB.