| Tag | Content |
|---|
| CPLM ID | CPLM-023680 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Long-chain fatty acid transport protein 6 |
Protein Synonyms/Alias | FATP-6; Fatty acid transport protein 6; Fatty-acid-coenzyme A ligase, very long-chain 2; Solute carrier family 27 member 6; Very long-chain acyl-CoA synthetase homolog 1; VLCSH1; hVLCS-H1 |
Gene Name | SLC27A6 |
Gene Synonyms/Alias | ACSVL2; FACVL2; FATP1 |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 196 | GVISLKEKLSTSPDE | ubiquitination | [1] |
|
Reference | [1] Systematic and quantitative assessment of the ubiquitin-modified proteome. Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP. Mol Cell. 2011 Oct 21;44(2):325-40. [ PMID: 21906983] |
Functional Description | Involved in translocation of long-chain fatty acids (LFCA) across the plasma membrane. Thought to function as the predominant fatty acid protein transporter in heart. |
Sequence Annotation | NP_BIND 221 232 AMP (Potential). |
Keyword | Cell membrane; Complete proteome; Fatty acid metabolism; Ligase; Lipid metabolism; Lipid transport; Membrane; Nucleotide-binding; Polymorphism; Reference proteome; Transmembrane; Transmembrane helix; Transport. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 619 AA |
Protein Sequence | MLLSWLTVLG AGMVVLHFLQ KLLFPYFWDD FWFVLKVVLI IIRLKKYEKR GELVTVLDKF 60
LSHAKRQPRK PFIIYEGDIY TYQDVDKRSS RVAHVFLNHS SLKKGDTVAL LMSNEPDFVH 120
VWFGLAKLGC VVAFLNTNIR SNSLLNCIRA CGPRALVVGA DLLGTVEEIL PSLSENISVW 180
GMKDSVPQGV ISLKEKLSTS PDEPVPRSHH VVSLLKSTCL YIFTSGTTGL PKAAVISQLQ 240
VLRGSAVLWA FGCTAHDIVY ITLPLYHSSA AILGISGCVE LGATCVLKKK FSASQFWSDC 300
KKYDVTVFQY IGELCRYLCK QSKREGEKDH KVRLAIGNGI RSDVWREFLD RFGNIKVCEL 360
YAATESSISF MNYTGRIGAI GRTNLFYKLL STFDLIKYDF QKDEPMRNEQ GWCIHVKKGE 420
PGLLISRVNA KNPFFGYAGP YKHTKDKLLC DVFKKGDVYL NTGDLIVQDQ DNFLYFWDRT 480
GDTFRWKGEN VATTEVADVI GMLDFIQEAN VYGVAISGYE GRAGMASIIL KPNTSLDLEK 540
VYEQVVTFLP AYACPRFLRI QEKMEATGTF KLLKHQLVED GFNPLKISEP LYFMDNLKKS 600
YVLLTRELYD QIMLGEIKL 619 |
Gene Ontology | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. GO:0005886; C:plasma membrane; TAS:Reactome. GO:0042383; C:sarcolemma; IEA:UniProtKB-SubCell. GO:0004467; F:long-chain fatty acid-CoA ligase activity; TAS:ProtInc. GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW. GO:0031957; F:very long-chain fatty acid-CoA ligase activity; IEA:Compara. GO:0015909; P:long-chain fatty acid transport; TAS:Reactome. GO:0055085; P:transmembrane transport; TAS:Reactome. GO:0000038; P:very long-chain fatty acid metabolic process; TAS:ProtInc. |
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