CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-024042
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Soluble lamin-associated protein of 75 kDa 
Protein Synonyms/Alias
 SLAP75; Protein FAM169A 
Gene Name
 FAM169A 
Gene Synonyms/Alias
 KIAA0888 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
226SLMYTACKQYFEKYPubiquitination[1, 2]
309QLTIDSLKDAFASTSubiquitination[3]
Reference
 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [2] hCKSAAP_UbSite: improved prediction of human ubiquitination sites by exploiting amino acid pattern and properties.
 Chen Z, Zhou Y, Song J, Zhang Z.
 Biochim Biophys Acta. 2013 Aug;1834(8):1461-7. [PMID: 23603789]
 [3] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983] 
Functional Description
  
Sequence Annotation
 MOD_RES 449 449 Phosphoserine.
 MOD_RES 635 635 Phosphoserine.
 MOD_RES 636 636 Phosphoserine (By similarity).
 MOD_RES 637 637 Phosphoserine (By similarity).  
Keyword
 Alternative splicing; Complete proteome; Membrane; Nucleus; Phosphoprotein; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 670 AA 
Protein Sequence
MAFPVDMLEN CSHEELENSA EDYMSDLRCG DPENPECFSL LNITIPISLS NVGFVPLYGG 60
DQTQKILALF APEDSLTAVA LYLADQWWAI DDIVKTSVPS REGLKQVSTL GERVVLYVLN 120
RIIYRKQEME RNEIPFLCHS STDYAKILWK KGEAIGFYSV KPTGSICASF LTQSYQLPVL 180
DTMFLRKKYR GKDFGLHMLE DFVDSFTEDA LGLRYPLSSL MYTACKQYFE KYPGDHELLW 240
EVEGVGHWYQ RIPVTRALQR EALKILALSQ NEPKRPMSGE YGPASVPEYE ARTEDNQSSE 300
MQLTIDSLKD AFASTSEGHD KTSVSTHTRS GNLKRPKIGK RFQDSEFSSS QGEDEKTSQT 360
SLTASINKLE STARPSESSE EFLEEEPEQR GIEFEDESSD RDARPALETQ PQQEKQDGEK 420
ESELEPMNGE IMDDSLKTSL ITEEEDSTSE VLDEELKLQP FNSSEDSTNL VPLVVESSKP 480
PEVDAPDKTP RIPDSEMLMD EGTSDEKGHM EEKLSLLPRK KAHLGSSDNV ATMSNEERSD 540
GGFPNSVIAE FSEEPVSENL SPNTTSSLED QGEEGVSEPQ ETSTALPQSS LIEVELEDVP 600
FSQNAGQKNQ SEEQSEASSE QLDQFTQSAE KAVDSSSEEI EVEVPVVDRR NLRRKAKGHK 660
GPAKKKAKLT 670 
Gene Ontology
 GO:0005637; C:nuclear inner membrane; IEA:UniProtKB-SubCell. 
Interpro
  
Pfam
  
SMART
  
PROSITE
  
PRINTS