CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-038612
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Intraflagellar transport protein 122 homolog 
Protein Synonyms/Alias
  
Gene Name
 Ift122 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
271SFYQLSGKQIGKDRPubiquitination[1]
753ETKMLITKQADWARNubiquitination[1]
1034QIPARIQKSIELGTLubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome; Repeat; WD repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1242 AA 
Protein Sequence
MRAVLTWRDK AEQCIYDLAF KPDGTQLILA AGNRLLVYDT SDGTLLQPLK GHKDTVYCVA 60
YAKDGKRFAS GSADKSIIIW TSKLEGILKY THNDSIQCVS YNPVTHQLAS CSSSDFGLWS 120
PEQKSVSKHK SSSKITCCSW TNDGQYLALG MANGIISIRN KNGEEKVKIE RPGGSLSPIW 180
SICWNPSSRW ETIWMSRENE DAEDVIVNKY VQEIPSILKS TVYNSQGSEA EEEEQEEEDD 240
SPRDGNSEEH NDILAVADWG QKLSFYQLSG KQIGKDRPLN FDPCCISYFT KGEYILVGGS 300
DKQVSLFTKD GVRLGTVGEQ NSWVWTCRVK PDSNYVVVGC QDGTISFYQL IFSTVHGLYK 360
DRYAYRDSMT DVIVQHLITE QKVRIKCREL VKKIAIYKNR LAIQLPEKIL IYELYSEDST 420
DMHYRVKEKI VKKFECNLLV VCADHIILCQ EKRLQCLSFS GVKEREWQME SLIRYIKVIG 480
GPAGREGLLV GLKNGQILKI FVDNLFAIVL LKQATAVRCL DMSASRNKLA VVDENDTCLV 540
YDIHTKELLF QEPNANSVAW NTQCEDMLCF SGGGYLNIKA STFPVHQQKL QGFVVGYNGS 600
KIFCLHVFSM SAVEVPQSAP MYQYLDRKMF KEAYQIACLG VTDADWRELA MEALEGLEFE 660
TARKAFTRVQ DLRYLELISS IEERKKRGET NNDLFLADVF SYQGKFHEAA KLYKRSGHEN 720
LALDMYTDLC MFEYAKDFLG SGDPKETKML ITKQADWARN INEPKAAVEM YISAGEHAKA 780
IEISGSHGWV DMLIDIARKL DKAEREPLLM CACYFKKLDS PGYAAETYLK IGDLKSLVQL 840
YVDTKRWDEA FALGEKHPEF KDDVYVPYAQ WLAENDRFEE AQKAFHKAGR QGEAVRVLEQ 900
LTHNAVVESR FNDAAYYYWM LSMQCLDMAQ DPAQKDAMLD KFHHFQHLAE LYHGYQTIHR 960
YTEEPFSFDL PETLFNISKF LLHSLTKATP LGISKVRNTL FTLAKQSKAL GAYKLARHAY 1020
DKLRGLQIPA RIQKSIELGT LTIRSKPFHD SEELVPLCYR CSTNNPLLNN LGNVCINCRQ 1080
PFIFSASSYE VLHLVEFYLE EGITDEEAVA LIDLEAPRHK REGKWRETSS NNSQTLKLDE 1140
TMDSIGEDDP FTAKLSFEQG SSEFVPVVVN RSVLRSMSRR DVLIKRWPPP LQWQYFRSLL 1200
PDASITMCPS CFQMFHSEDY ELLVLQHACC PYCRRRIDDT GP 1242 
Gene Ontology
 GO:0005737; C:cytoplasm; ISS:MGI.
 GO:0060830; P:ciliary receptor clustering involved in smoothened signaling pathway; IGI:MGI.
 GO:0060271; P:cilium morphogenesis; IGI:MGI.
 GO:0042733; P:embryonic digit morphogenesis; IMP:MGI.
 GO:0060831; P:smoothened signaling pathway involved in dorsal/ventral neural tube patterning; IGI:MGI. 
Interpro
 IPR011990; TPR-like_helical.
 IPR015943; WD40/YVTN_repeat-like_dom.
 IPR001680; WD40_repeat.
 IPR017986; WD40_repeat_dom. 
Pfam
 PF00400; WD40 
SMART
 SM00320; WD40 
PROSITE
 PS50082; WD_REPEATS_2
 PS50294; WD_REPEATS_REGION 
PRINTS