Tag | Content |
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CPLM ID | CPLM-023052 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Oxidative stress-induced growth inhibitor 1 |
Protein Synonyms/Alias | Ovary, kidney and liver protein 38; huOKL38; Pregnancy-induced growth inhibitor OKL38 |
Gene Name | OSGIN1 |
Gene Synonyms/Alias | OKL38 |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
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56 | PHPLLQRKLTEAPGV | ubiquitination | [1] | 331 | LVFNQLPKMLYPEYH | ubiquitination | [1] |
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Reference | [1] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization. Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW. Nature. 2013 Apr 18;496(7445):372-6. [ PMID: 23503661] |
Functional Description | Regulates the differentiation and proliferation of normal cells through the regulation of cell death. |
Sequence Annotation | |
Keyword | Alternative splicing; Complete proteome; Developmental protein; Differentiation; Growth regulation; Polymorphism; Reference proteome. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 560 AA |
Protein Sequence | MSSSRKDHLG ASSSEPLPVI IVGNGPSGIC LSYLLSGYTP YTKPDAIHPH PLLQRKLTEA 60 PGVSILDQDL DYLSEGLEGR SQSPVALLFD ALLRPDTDFG GNMKSVLTWK HRKEHAIPHV 120 VLGRNLPGGA WHSIEGSMVI LSQGQWMGLP DLEVKDWMQK KRRGLRNSRA TAGDIAHYYR 180 DYVVKKGLGH NFVSGAVVTA VEWGTPDPSS CGAQDSSPLF QVSGFLTRNQ AQQPFSLWAR 240 NVVLATGTFD SPARLGIPGE ALPFIHHELS ALEAATRVGA VTPASDPVLI IGAGLSAADA 300 VLYARHYNIP VIHAFRRAVD DPGLVFNQLP KMLYPEYHKV HQMMREQSIL SPSPYEGYRS 360 LPRHQLLCFK EDCQAVFQDL EGVEKVFGVS LVLVLIGSHP DLSFLPGAGA DFAVDPDQPL 420 SAKRNPIDVD PFTYQSTRQE GLYAMGPLAG DNFVRFVQGG ALAVASSLLR KETRKPP 477 |
Gene Ontology | GO:0008083; F:growth factor activity; IDA:UniProtKB. GO:0030154; P:cell differentiation; IEA:UniProtKB-KW. GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW. GO:0030308; P:negative regulation of cell growth; IDA:UniProtKB. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |