CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-008335
UniProt Accession
Genbank Protein ID
 X82180 
Genbank Nucleotide ID
Protein Name
 60S ribosomal protein L4 
Protein Synonyms/Alias
 60S ribosomal protein L1 
Gene Name
 Rpl4 
Gene Synonyms/Alias
 Rpl1 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
14LISVYSEKGESSGKNacetylation[1]
29VTLPAVFKAPIRPDIacetylation[1]
106GRMFAPTKTWRRWHRacetylation[1]
172KEAVQLLKKLKAWNDacetylation[1]
181LKAWNDIKKVYASQRacetylation[1]
239VSKLNILKLAPGGHVacetylation[1]
364AAAALAAKSEKIVPEubiquitination[2]
367ALAAKSEKIVPEKGAacetylation[1]
383DKKPAVGKKGKKPVDacetylation[1]
384KKPAVGKKGKKPVDAacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405]
 [2] Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis.
 Na CH, Jones DR, Yang Y, Wang X, Xu Y, Peng J.
 J Proteome Res. 2012 Sep 7;11(9):4722-32. [PMID: 22871113] 
Functional Description
  
Sequence Annotation
 MOD_RES 2 2 N-acetylalanine (By similarity).
 MOD_RES 14 14 N6-acetyllysine (By similarity).
 MOD_RES 106 106 N6-acetyllysine (By similarity).
 MOD_RES 295 295 Phosphoserine (By similarity).
 MOD_RES 333 333 N6-acetyllysine (By similarity).
 MOD_RES 365 365 Phosphoserine (By similarity).  
Keyword
 Acetylation; Complete proteome; Phosphoprotein; Reference proteome; Ribonucleoprotein; Ribosomal protein. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 421 AA 
Protein Sequence
MACARPLISV YSEKGESSGK NVTLPAVFKA PIRPDIVNFV HTNLRKNNRQ PYAVSELAGH 60
QTSAESWGTG RAVARIPRVR GGGTHRSGQG AFGNMCRGGR MFAPTKTWRR WHRRVNTTQK 120
RYAICSALAA SALPALVMSK GHCVEEVPEL PLVVEDKVES YKKTKEAVQL LKKLKAWNDI 180
KKVYASQRMR AGKGKMRNRR RIQRRGPCII YNEDNGIIKA FRNIPGITLL NVSKLNILKL 240
APGGHVGRFC IWTESAFRKL DELYGTWRKA ASLKSNYNLP MHKMMNTDLS RILKSPEIQR 300
ALRAPRKKIH RRVLKKNPLK NLRIMLKLNP YAKTMRRNTI LRQARNHKLR VKKLEAAAAA 360
LAAKSEKIVP EKGAGDKKPA VGKKGKKPVD AKKLKKPAGK KVVTKKPAEK KPTTEEKKSA 420
A 421 
Gene Ontology
 GO:0015934; C:large ribosomal subunit; IDA:UniProtKB.
 GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
 GO:0006412; P:translation; IEA:InterPro. 
Interpro
 IPR025755; Ribos_L4_C_dom.
 IPR002136; Ribosomal_L4/L1e.
 IPR013000; Ribosomal_L4/L1e_euk/arc_CS.
 IPR023574; Ribosomal_L4_dom. 
Pfam
 PF14374; Ribos_L4_asso_C
 PF00573; Ribosomal_L4 
SMART
  
PROSITE
 PS00939; RIBOSOMAL_L1E 
PRINTS