UniProt Accession

 I3L2B0_HUMAN; I3L2B0 

Genbank Protein ID

 AC005696 

Genbank Nucleotide ID

  

Protein Name

 Clustered mitochondria protein homolog 

Protein Synonyms/Alias

  

Gene Name

 CLUH 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
213	GDSGKRKKGLEMDPI	ubiquitination	[1]
248	QPQNRDWKPLQCLKV	ubiquitination	[1]
333	QISPTFKKNFAVLQK	ubiquitination	[1]
341	NFAVLQKKRVQRHPF	ubiquitination	[1]
475	FDVRDHYKDFGGDVA	ubiquitination	[1]
567	ERTSRPLKILRHQVL	ubiquitination	[1, 2]
590	LCSSVECKGIIGNDG	ubiquitination	[2, 3]
714	SSASGLAKVKELAET	ubiquitination	[3]
742	EVIRNACKAVGSISS	ubiquitination	[1, 4]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094]
 [3] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [4] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302] 

Functional Description

 Involved in proper cytoplasmic distribution of mitochondria (By similarity). 

Sequence Annotation

  

Keyword

 Complete proteome; Cytoplasm; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 769 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IEA:UniProtKB-KW. 

Interpro

 IPR025697; CLU_dom.
 IPR023231; GSKIP/TIF31_domain. 

Pfam

 PF13236; CLU 

SMART

  

PROSITE

  

PRINTS