CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-002410
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 HTH-type transcriptional regulator DicA 
Protein Synonyms/Alias
 Repressor protein of division inhibition gene dicA 
Gene Name
 dicA 
Gene Synonyms/Alias
 b1570; JW1562 
Created Date
 July 27, 2013 
Organism
 Escherichia coli (strain K12) 
NCBI Taxa ID
 83333 
Lysine Modification
Position
Peptide
Type
References
50GDSEPTGKNLFALSKacetylation[1]
73ILFGDEDKQPTPPVEacetylation[1]
81QPTPPVEKPVALSPKacetylation[1]
120ARVKNFNKLFEELLKacetylation[1]
127KLFEELLKARQRTNKacetylation[1]
Reference
 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618
Functional Description
 This protein is a repressor of division inhibition gene dicB. 
Sequence Annotation
 DOMAIN 12 66 HTH cro/C1-type.
 DNA_BIND 23 42 H-T-H motif (Potential).  
Keyword
 Cell cycle; Cell division; Complete proteome; DNA-binding; Reference proteome; Repressor; Transcription; Transcription regulation. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 135 AA 
Protein Sequence
METKNLTIGE RIRYRRKNLK HTQRSLAKAL KISHVSVSQW ERGDSEPTGK NLFALSKVLQ 60
CSPTWILFGD EDKQPTPPVE KPVALSPKEL ELLELFNALP ESEQDTQLAE MRARVKNFNK 120
LFEELLKARQ RTNKR 135 
Gene Ontology
 GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
 GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
 GO:0051301; P:cell division; IEA:UniProtKB-KW.
 GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.
 GO:0006351; P:transcription, DNA-dependent; IGI:EcoCyc. 
Interpro
 IPR001387; HTH.
 IPR010982; Lambda_DNA-bd_dom. 
Pfam
 PF01381; HTH_3 
SMART
 SM00530; HTH_XRE 
PROSITE
 PS50943; HTH_CROC1 
PRINTS