| Tag | Content |
|---|
| CPLM ID | CPLM-024077 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Solute carrier family 13 member 3 |
Protein Synonyms/Alias | Na(+)/dicarboxylate cotransporter 3; NaDC-3; rNaDC3; Sodium-dependent high-affinity dicarboxylate transporter 2 |
Gene Name | Slc13a3 |
Gene Synonyms/Alias | Nadc3; Sdct2 |
Created Date | July 27, 2013 |
Organism | Rattus norvegicus (Rat) |
NCBI Taxa ID | 10116 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 321 | LQDVAEDKAKAVIQE | ubiquitination | [1] |
|
Reference | [1] Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis. Na CH, Jones DR, Yang Y, Wang X, Xu Y, Peng J. J Proteome Res. 2012 Sep 7;11(9):4722-32. [ PMID: 22871113] |
Functional Description | High-affinity sodium-dicarboxylate cotransporter that accepts a range of substrates with 4-5 carbon atoms. The stoichiometry is probably 3 Na(+) for 1 divalent succinate. |
Sequence Annotation | CARBOHYD 584 584 N-linked (GlcNAc...) (Potential).
CARBOHYD 594 594 N-linked (GlcNAc...) (Potential). |
Keyword | Cell membrane; Complete proteome; Glycoprotein; Ion transport; Membrane; Reference proteome; Sodium; Sodium transport; Symport; Transmembrane; Transmembrane helix; Transport. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 600 AA |
Protein Sequence | MAALAALAKK VWSARRLLVL LLVPLALLPI LFALPPKEGR CLYVILLMAV YWCTEALPLS 60
VTALLPIILF PFMGILPSSK VCPQYFLDTN FLFLSGLIMA SAIEERNLHR RIALKVLMLV 120
GVQPARLILG MMVTTSFLSM WLSNTASTAM MLPIASAILK SLFGQRDTRK DLPREGEDST 180
AAVRGNGLRT VPTEMQFLAS SEGGHAEDVE APLELPDDSK EEEHRRNIWK GFLISIPYSA 240
SIGGTATLTG TAPNLILLGQ LKSFFPQCDV VNFGSWFIFA FPLMLLFLLV GWLWISFLYG 300
GMSWRGWRKK NSKLQDVAED KAKAVIQEEF QNLGPIKFAE QAVFILFCLF AILLFSRDPK 360
FIPGWASLFA PGFVSDAVTG VAIVTILFFF PSQKPSLKWW FDFKAPNSET EPLLSWKKAQ 420
ETVPWNIILL LGGGFAMAKG CEESGLSAWI GGQLHPLEHV PPLLAVLLIT VVIAFFTEFA 480
SNTATIIIFL PVLAELAIRL HVHPLYLMIP GTVSCSYAFM LPVSTPPNSI AFSTGHLLVK 540
DMVRTGLLMN LMGVLLLSLA MNTWAQAIFQ LGTFPDWANT HAANVTALPP ALTNNTVQTL 600 |
Gene Ontology | GO:0016021; C:integral to membrane; IDA:RGD. GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. GO:0015137; F:citrate transmembrane transporter activity; IDA:RGD. GO:0015183; F:L-aspartate transmembrane transporter activity; IDA:RGD. GO:0017153; F:sodium:dicarboxylate symporter activity; IDA:RGD. GO:0015141; F:succinate transmembrane transporter activity; IDA:RGD. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |