CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-013842
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Multiple C2 and transmembrane domain-containing protein 2 
Protein Synonyms/Alias
  
Gene Name
 Mctp2 
Gene Synonyms/Alias
 Gm489 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
335RKRLSASKSSLIRNLubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
 DOMAIN 181 276 C2 1.
 DOMAIN 343 436 C2 2.
 DOMAIN 496 591 C2 3.  
Keyword
 Calcium; Complete proteome; Membrane; Reference proteome; Repeat; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 878 AA 
Protein Sequence
MDLDKPSVWG SLKQRTRPLL INLSKKKAKK SPSKPLDLRV QHHLDRRLSL SVPDLLEAEA 60
LAPEGRPYSG PQSSYISVPN SLSTAGIVPK SSSSSLKQSE EELDWSQEEA SHVHGVDTDS 120
EEIYASPAEE WQAFSQSALD LHKPSLGRDA PEEHDKTHGN DDLNASMTSQ HFEEESTLGE 180
ASDCVSHLPS PFAYLLTIHL KEGRNLVVRD RCGTSDPYVK FKLNGKTLYK SKVIYKNLNP 240
IWDEIVVLPI QSLDQKLRVK VYDRDLTKSD FMGSAFVVLR DLELNRTTEH ILKLEDPNSL 300
EDDMGVIVLN LNLVVKQGDF KRHRWSNRKR LSASKSSLIR NLRLSESLRK NQLWNGIISI 360
TLLEGKNVSG GNMTEMFVQL KLGEQRYKSK TLCKSANPQW QEQFDFHYFS DRMGILDIEV 420
WGKDSKKHEE RLGTCKVDIS ALPLKQDNCL ELPLESCQGA LLMLITLTPC TGVSISDLCV 480
CPFEDPSERQ QISQRYAFQN SLKDVKDVGI LQVKVLKASD LLAADFSGKS DPFCLLELGN 540
DRLQTHTIYK NLNPEWNKVF TFPIKDIHDV LEVTVFDEDG DKAPDFLGKV AIPLLSIRDG 600
QPNCYVLKNK DLEQAFKGLI YLELDLIYNP VKASIRTFTP REKRFVEDSR KLSKKILSRD 660
VDRVKRLTLA IWNTVQFFKS CFQWESTLRS TIAFVVFLVT VWNFELYMIP LALLLLFLYN 720
FLRPMKGKAS STQDSQESTD VEEEGKEEEK ESEKKGIIER IYMVQDIVST VQNILEEVAS 780
FGERIKNVFN WTVPFLSLLA CLILAITTVI LYFIPLRYII LLWGINKFTK KLRNPYSIDN 840
NELLDFLSRV PSDIQKVQYA ELKLCGSHSP LRKKRSTV 878 
Gene Ontology
 GO:0016021; C:integral to membrane; ISS:HGNC.
 GO:0005509; F:calcium ion binding; ISS:HGNC. 
Interpro
 IPR000008; C2_Ca-dep.
 IPR008973; C2_Ca/lipid-bd_dom_CaLB.
 IPR018029; C2_membr_targeting.
 IPR013583; PRibTrfase_C. 
Pfam
 PF00168; C2
 PF08372; PRT_C 
SMART
 SM00239; C2 
PROSITE
 PS50004; C2 
PRINTS