CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-024560
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 UPF0249 protein ydjC homolog 
Protein Synonyms/Alias
  
Gene Name
 YDJC 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
92PEGFFLGKMGFREAVubiquitination[1, 2, 3, 4, 5]
302ALDDLDSKRPGEEVPubiquitination[3]
Reference
 [1] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094]
 [2] Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition.
 Udeshi ND, Mani DR, Eisenhaure T, Mertins P, Jaffe JD, Clauser KR, Hacohen N, Carr SA.
 Mol Cell Proteomics. 2012 May;11(5):148-59. [PMID: 22505724]
 [3] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [4] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661]
 [5] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302
Functional Description
  
Sequence Annotation
  
Keyword
 Alternative splicing; Complete proteome; Polymorphism; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 323 AA 
Protein Sequence
MSRPRMRLVV TADDFGYCPR RDEGIVEAFL AGAVTSVSLL VNGAATESAA ELARRHSIPT 60
GLHANLSEGR PVGPARRGAS SLLGPEGFFL GKMGFREAVA AGDVDLPQVR EELEAQLSCF 120
RELLGRAPTH ADGHQHVHVL PGVCQVFAEA LQAYGVRFTR LPLERGVGGC TWLEAPARAF 180
ACAVERDARA AVGPFSRHGL RWTDAFVGLS TCGRHMSAHR VSGALARVLE GTLAGHTLTA 240
ELMAHPGYPS VPPTGGCGEG PDAFSCSWER LHELRVLTAP TLRAQLAQDG VQLCALDDLD 300
SKRPGEEVPC EPTLEPFLEP SLL 323 
Gene Ontology
 GO:0016810; F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds; IEA:InterPro.
 GO:0005975; P:carbohydrate metabolic process; IEA:InterPro. 
Interpro
 IPR002509; Polysac_deacetylase.
 IPR006879; Uncharacterised_UPF0249/HpnK. 
Pfam
 PF04794; YdjC 
SMART
  
PROSITE
  
PRINTS