| Tag | Content |
|---|
| CPLM ID | CPLM-010852 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | DNA polymerase alpha-binding protein |
Protein Synonyms/Alias | Chromosome replication protein CHL15; Chromosome transmission fidelity protein 4; Protein POB1 |
Gene Name | CTF4 |
Gene Synonyms/Alias | CHL15; POB1; YPR135W; P9659.7 |
Created Date | July 27, 2013 |
Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
NCBI Taxa ID | 559292 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 40 | NGLTKILKTNNPEEE | ubiquitination | [1] |
|
Reference | [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation. Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J. Nat Methods. 2013 Jul;10(7):676-82. [ PMID: 23749301] |
Functional Description | Accessory factor for DNA replication. It plays a role in accurately duplicating the genome in vivo. |
Sequence Annotation | REPEAT 10 49 WD 1.
REPEAT 134 173 WD 2.
REPEAT 227 266 WD 3.
REPEAT 273 313 WD 4.
REPEAT 699 739 WD 5.
MOD_RES 377 377 Phosphoserine.
MOD_RES 379 379 Phosphoserine.
MOD_RES 398 398 Phosphoserine.
MOD_RES 401 401 Phosphothreonine.
MOD_RES 411 411 Phosphothreonine.
MOD_RES 463 463 Phosphoserine. |
Keyword | Complete proteome; Direct protein sequencing; DNA replication; Nucleus; Phosphoprotein; Reference proteome; Repeat; WD repeat. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 927 AA |
Protein Sequence | MVSVIDKLVF DFGGKTLVSL APDNNTLCVA NKNGLTKILK TNNPEEEPET LDSSKLVSSI 60
KCYSNSHFLM TTMQGDALRY NIDSSQEELL ARFALPLRDC CVIHSGKMAV FGGDDLELIL 120
LELDDETHKK HAIKIDEQVS QISYNSQMNI LAVSMINGKV QIFSLTSTIP NKVHELNDYI 180
VANSYDDTHR DKILSNMMDD IDKDNDNDLS ETADPDENNV ADPEFCAANR ICTRVAWHPK 240
GLHFALPCAD DTVKIFSIKG YSLQKTLSTN LSSTKAHFID LQFDPLRGTY IAAVDLNNKL 300
TVWNWETSEI HYTREFKRKI TNIAWKIQAD SKTLDLVLGT WSGSIAIVQN LAESVVSNIP 360
DQSVAESSTK HGLFVDSESD LENLEGNDDI NKSDKLFSDI TQEANAEDVF TQTHDGPSGL 420
SEKRKYNFED EEDFIDDDDG AGYISGKKPH NEHSYSRVHK THSFPISLAN TGKFRYMPFS 480
PAGTPFGFTD RRYLTMNEVG YVSTVKNSEQ YSITVSFFDV GRFREYHFED LFGYDLCFLN 540
EKGTLFGQSK TGQIQYRPHD SIHSNWTKII PLQAGERITS VAATPVRVIV GTSLGYFRSF 600
NQFGVPFAVE KTSPIVALTA QNYRVFSVHY SQFHGLSYSL SELGTSSKRY YKRECPLPMS 660
LPNINSDMKK DANLDYYNFN PMGIKSLFFS SYGDPCIFGS DNTLLLLSKW RSPEESKWLP 720
ILDSNMEIWK MSGGKETTDI HVWPLALAYD TLNCILVKGK HIWPEFPLPL PSEMEIRMPV 780
FVKSKLLEEN KAILNKKNEI GADTEAEEGE EDKEIQIPVS MAAEEEYLRS KVLSELLTDT 840
LENDGEMYGN ENEVLAALNG AYDKALLRLF ASACSDQNVE KALSLAHELK QDRALTAAVK 900
ISERAELPSL VKKINNIREA RYEQQLK 927 |
Gene Ontology | GO:0031298; C:replication fork protection complex; IDA:SGD. GO:0003682; F:chromatin binding; IDA:SGD. GO:0003677; F:DNA binding; ISS:SGD. GO:0006270; P:DNA replication initiation; IMP:SGD. GO:0000727; P:double-strand break repair via break-induced replication; IMP:SGD. GO:0007064; P:mitotic sister chromatid cohesion; IMP:SGD. GO:0001302; P:replicative cell aging; IMP:SGD. |
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Pfam | |
SMART | |
PROSITE | |
PRINTS | |