CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-025854
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 BRCA1 associated protein variant 
Protein Synonyms/Alias
  
Gene Name
  
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
425VASKTDGKIVQYECEubiquitination[1]
Reference
 [1] Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass.
 Povlsen LK, Beli P, Wagner SA, Poulsen SL, Sylvestersen KB, Poulsen JW, Nielsen ML, Bekker-Jensen S, Mailand N, Choudhary C.
 Nat Cell Biol. 2012 Oct;14(10):1089-98. [PMID: 23000965] 
Functional Description
  
Sequence Annotation
  
Keyword
 Metal-binding; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 632 AA 
Protein Sequence
GGGNCIEVVA ALPAPGRSAS RLAFQPRLSP PGPAPASACP MSVSLVVIRL ELAEHSPVPA 60
GFGFSAAAGE MSDEEIKKTT LASAVACLEG KSPGEKVAII HQHLGRREMT DVIIETMKSN 120
PDELKTTVEE RKSSEASPTA QRSKDHSKEC INAAPDSPSK QLPDQISFFS GNPSVEIVHG 180
IMHLYKTNKM TSLKEDVRRS AMLCILTVPA AMTSHDLMKF VAPFNEVIEQ MKIIRDSTPN 240
QYMVLIKFRA QADADSFYMT CNGRQFNSIE DDVCQLVYVE RAEVLKSEDG ASLPVMDLTE 300
LPKCTVCLER MDESVNGILT TLCNHSFHSQ CLQRWDDTTC PVCRYCQTPE PVEENKCFEC 360
GVQENLWICL ICGHIGCGRY VSRHAYKHFE ETQHTYAMQL TNHRVWDYAG DNYVHRLVAS 420
KTDGKIVQYE CEGDTCQEEK IDALQLEYSY LLTSQLESQR IYWENKIVRI EKDTAEEINN 480
MKTKFKETIE KCDNLEHKLN DLLKEKQSVE RKCTQLNTKV AKLTNELKEE QEMNKCLRAN 540
QVLLQNKLKE EERVLKETCD QKDLQITEIQ EQLRDVMFYL ETQQKINHLP AETRQEIQEG 600
QINIAMASAS SPASSGGSGK LPSRKGRSKR GK 632 
Gene Ontology
 GO:0005737; C:cytoplasm; IDA:HPA.
 GO:0031965; C:nuclear membrane; IDA:HPA.
 GO:0000166; F:nucleotide binding; IEA:InterPro.
 GO:0008270; F:zinc ion binding; IEA:InterPro. 
Interpro
 IPR011422; BRAP2.
 IPR012677; Nucleotide-bd_a/b_plait.
 IPR001841; Znf_RING.
 IPR013083; Znf_RING/FYVE/PHD.
 IPR001607; Znf_UBP. 
Pfam
 PF07576; BRAP2
 PF13639; zf-RING_2
 PF02148; zf-UBP 
SMART
 SM00184; RING
 SM00290; ZnF_UBP 
PROSITE
 PS50089; ZF_RING_2
 PS50271; ZF_UBP 
PRINTS