| Tag | Content |
|---|
| CPLM ID | CPLM-000169 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Calpain-5 |
Protein Synonyms/Alias | New calpain 3; nCL-3 |
Gene Name | Capn5 |
Gene Synonyms/Alias | Ncl3 |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 24 | KRACLRKKVLFEDPL | ubiquitination | [1] | | 42 | TDDSLYYKGTPGPTV | ubiquitination | [1] | | 339 | RYFTDIIKCRLINTS | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | |
Sequence Annotation | DOMAIN 26 343 Calpain catalytic.
DOMAIN 518 619 C2.
REGION 344 496 Domain III.
ACT_SITE 81 81 By similarity.
ACT_SITE 252 252 By similarity.
ACT_SITE 284 284 By similarity. |
Keyword | Complete proteome; Hydrolase; Polymorphism; Protease; Reference proteome; Thiol protease. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 640 AA |
Protein Sequence | MFSCAKAYED QNYSALKRAC LRKKVLFEDP LFPATDDSLY YKGTPGPTVR WKRPKDICDD 60
PRLFVDGISS HDLHQGQVGN CWFVAACSSL ASRESLWQKV IPDWKEQEWN PEKPDSYAGI 120
FHFNFWRFGE WVDVIVDDRL PTVNNQLIYC HSNSKNEFWC ALVEKAYAKL AGCYQALDGG 180
NTADALVDFT GGVSEPIDLT EGDLATDEAK RNQLFERVLK VHSRGGLISA SIKAVTAADM 240
EARLACGLVK GHAYAVTDVR KVRLGHGLLA FFKSEKLDMI RLRNPWGERE WTGPWSDTSE 300
EWQKVSKSER EKMGVTVQDD GEFWMTFEDM CRYFTDIIKC RLINTSYLSI HKTWEEARLH 360
GAWTRHEDPQ QNRSGGCINH KDTFFQNPQY VFEVKKPEDE VLISIQQRPK RSTRREGKGE 420
NLAIGFDIYK VEENRQYRMH SLQHKAASSI YINSRSVFLR TELPEGRYVI IPTTFEPGHT 480
GEFLLRVFTD VPSNCRELRL DEPPRTCWSS LCGYPQQVAQ VHVLGAAGLK DSPTGANSYV 540
IIKCEGEKVR SAVQRGTSTP EYNVKGIFYR KKLAQPITVQ VWNHRVLKDE FLGQVHLKTA 600
PDDLQDLHTL HLQDRSSRQP SDLPGIVAVR VLCSASLTAV 640 |
Gene Ontology | GO:0009986; C:cell surface; ISS:UniProtKB. GO:0005622; C:intracellular; IEA:InterPro. GO:0004198; F:calcium-dependent cysteine-type endopeptidase activity; IEA:InterPro. GO:0006508; P:proteolysis; IEA:UniProtKB-KW. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |