CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-035014
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Ubiquitin carboxyl-terminal hydrolase 
Protein Synonyms/Alias
  
Gene Name
 Usp20 
Gene Synonyms/Alias
 Usp20_predicted; rCG_45810 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
907ESLHGEQKIEAETRAubiquitination[1]
Reference
 [1] Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis.
 Na CH, Jones DR, Yang Y, Wang X, Xu Y, Peng J.
 J Proteome Res. 2012 Sep 7;11(9):4722-32. [PMID: 22871113] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Hydrolase; Metal-binding; Protease; Reference proteome; Thiol protease; Ubl conjugation pathway; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 915 AA 
Protein Sequence
MGDARDICPH LDSIGEVTKE DLLLKSKGTC QSCGVAGPNL WACLQVTCPY VGCGESFADH 60
SSIHAQVKRH NLTVNLTTLR VWCYACEREV FLEQRLAVHL PSSSARLSEQ DSPPPCHPLK 120
AVPIAVADEG ESESEDDDLK PRGLTGMKNL GNSCYMNAAL QALSNCPPLT QFFLECGGLV 180
RTDKKPALCK SYQKLISEVW HKKRPSYVVP TSLSHGIKLV NPMFRGYAQQ DTQEFLRCLM 240
DQLHEELKEP MVAAVAALTD ARDSDSSDTD ERRDGDRSPS EDEFLSCDSS SDRGEGDGQG 300
RGGGSSKAEM ELLISDEAGR AISEKERMKD RKFSWGQQRT NSEQVDEDAD VDTAMASLDE 360
QSREAQPPSP RPTSPCQTPE PDNEVHIRSS SRPCSPVHHH EGHTKLSSSP PRASPVRMGP 420
SYVLKKAQVP STGGRRRKEQ SYRSVISDVF NGSVLSLVQC LTCDRVSTTV ETFQDLSLPI 480
PGKEDLAKLH SAIYQNVPAK PGACGDSYSS QGWLAFIVEY IRRFVVSCTP SWFWGPVVTL 540
EDCLAAFFAA DELKGDNMYS CERCKKLRNG VKYCKVLCLP EILCVHLKRF RHEVMYSFKV 600
SSHVSFPLEG LDLRPFLAKE CTSQVTTYDL LSVICHHGTA GSGHYIAYCQ NVINGQWYEF 660
DDQYVTEVHE TVVQNVEAYV LFYRKSSEEA MRERQQVVSL AAMQEPSLLR FYVSREWLNK 720
FNTFAEPGPI TNHTFLCPHG GIPPNKYHYI DDLVVILPQS VWEHLYSRFG GGPAVNHLYV 780
CSICQVEIEA LAKRRRVEID TFIKLNKAFQ AEESPGVIYC ISMHWFREWE AFVKGKDSEP 840
PGPIDNSRIA QVKGSGHIQL KQGADYGQIS EETWTYLNSL YGGGPEIAIR QSVAQLPDPE 900
SLHGEQKIEA ETRAL 915 
Gene Ontology
 GO:0004197; F:cysteine-type endopeptidase activity; IEA:Compara.
 GO:0004221; F:ubiquitin thiolesterase activity; IEA:Compara.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0071108; P:protein K48-linked deubiquitination; IEA:Compara.
 GO:0070536; P:protein K63-linked deubiquitination; IEA:Compara.
 GO:0008277; P:regulation of G-protein coupled receptor protein signaling pathway; IEA:Compara.
 GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro. 
Interpro
 IPR006615; Pept_C19_DUSP.
 IPR018200; Pept_C19ubi-hydrolase_C_CS.
 IPR001394; Peptidase_C19.
 IPR013083; Znf_RING/FYVE/PHD.
 IPR001607; Znf_UBP. 
Pfam
 PF06337; DUSP
 PF00443; UCH
 PF02148; zf-UBP 
SMART
 SM00695; DUSP 
PROSITE
 PS51283; DUSP
 PS00972; UCH_2_1
 PS00973; UCH_2_2
 PS50235; UCH_2_3
 PS50271; ZF_UBP 
PRINTS