CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-006872
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Mitotic spindle-associated protein SHE1 
Protein Synonyms/Alias
 Sensitive to high expression protein 1 
Gene Name
 SHE1 
Gene Synonyms/Alias
 YBL031W; YBL0420 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
63LDSRASSKFEFLKDQacetylation[1]
Reference
 [1] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae.
 Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C.
 Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [PMID: 22865919] 
Functional Description
 May have a role related to the spindle integrity function of the DAM1 complex, which is essential for proper chromosome segregation. Causes growth arrest when highly overexpressed. 
Sequence Annotation
 MOD_RES 165 165 Phosphoserine.  
Keyword
 Cell cycle; Cell division; Chromosome partition; Complete proteome; Cytoplasm; Cytoskeleton; Mitosis; Phosphoprotein; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 338 AA 
Protein Sequence
MNDKLQEEHN EKDTTSQING FTPPHMSIDF HSNNNSNIIE TIGVSKRLGN SVLSELDSRA 60
SSKFEFLKDQ SEQQYNGDKN NEPKSGSYNI NEFFQAKHDS QFGQMESLDT HYTLLHTPKR 120
KSQHAIPQDR SDSMKRSRPS RSIPYTTPVV NDITRRIRRL KLRNSLVNGN DIVARARSMQ 180
ANSNINSIKN TPLSKPKPFM HKPNFLMPTT NSLNKINSAH RNTSSSSTAS SIPRSKVHRS 240
ISIRDLHAKT KPVERTPVAQ GTNSQLKNSV SVFDRLYKQT TFSRSTSMNN LSSGTSAKSK 300
EHTNVKTRLV KSKTSGSLSS NLKQSTATGT KSDRPIWR 338 
Gene Ontology
 GO:0005935; C:cellular bud neck; IDA:SGD.
 GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
 GO:0005880; C:nuclear microtubule; IDA:SGD.
 GO:0005819; C:spindle; IDA:SGD.
 GO:0008017; F:microtubule binding; IDA:SGD.
 GO:0051301; P:cell division; IEA:UniProtKB-KW.
 GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.
 GO:0007067; P:mitosis; IEA:UniProtKB-KW.
 GO:0000022; P:mitotic spindle elongation; IMP:SGD. 
Interpro
  
Pfam
  
SMART
  
PROSITE
  
PRINTS