UniProt Accession

 F6TGV1_MOUSE; F6TGV1 

Genbank Protein ID

 AL772285 

Genbank Nucleotide ID

  

Protein Name

 Exosome complex component RRP40 

Protein Synonyms/Alias

  

Gene Name

 Exosc3 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
63	LAFEGATKRNRPNVQ	ubiquitination	[1]
121	VTLGLIRKLLAPDCE	acetylation	[2]

Reference

 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023]
 [2] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 145 AA 

Protein Sequence

Gene Ontology

 GO:0000178; C:exosome (RNase complex); IEA:InterPro.
 GO:0003723; F:RNA binding; IEA:InterPro.
 GO:0045830; P:positive regulation of isotype switching; IMP:MGI. 

Interpro

 IPR026699; Exosome_RNA_bind1/RRP40/RRP4. 

Pfam

  

SMART

  

PROSITE

  

PRINTS